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A fast algorithm for determining bounds and accurate approximate p-values of the rank product statistic for replicate experiments
BACKGROUND: The rank product method is a powerful statistical technique for identifying differentially expressed molecules in replicated experiments. A critical issue in molecule selection is accurate calculation of the p-value of the rank product statistic to adequately address multiple testing. Bo...
Autores principales: | Heskes, Tom, Eisinga, Rob, Breitling, Rainer |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4245829/ https://www.ncbi.nlm.nih.gov/pubmed/25413493 http://dx.doi.org/10.1186/s12859-014-0367-1 |
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