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A fast algorithm for determining bounds and accurate approximate p-values of the rank product statistic for replicate experiments

BACKGROUND: The rank product method is a powerful statistical technique for identifying differentially expressed molecules in replicated experiments. A critical issue in molecule selection is accurate calculation of the p-value of the rank product statistic to adequately address multiple testing. Bo...

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Detalles Bibliográficos
Autores principales: Heskes, Tom, Eisinga, Rob, Breitling, Rainer
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4245829/
https://www.ncbi.nlm.nih.gov/pubmed/25413493
http://dx.doi.org/10.1186/s12859-014-0367-1

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