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Vitamin D regulating TGF-β induced epithelial-mesenchymal transition

BACKGROUND: Subepithelial fibrosis is a characteristic hallmark of airway remodeling in asthma. A critical regulator of fibrosis, transforming growth factor β (TGF-β), can induce airway remodeling in epithelial cells through induction of epithelial-mesenchymal transition (EMT). Vitamin D has immunom...

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Detalles Bibliográficos
Autores principales: Fischer, Kimberly D, Agrawal, Devendra K
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4245846/
https://www.ncbi.nlm.nih.gov/pubmed/25413472
http://dx.doi.org/10.1186/s12931-014-0146-6