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Vitamin D regulating TGF-β induced epithelial-mesenchymal transition
BACKGROUND: Subepithelial fibrosis is a characteristic hallmark of airway remodeling in asthma. A critical regulator of fibrosis, transforming growth factor β (TGF-β), can induce airway remodeling in epithelial cells through induction of epithelial-mesenchymal transition (EMT). Vitamin D has immunom...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2014
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4245846/ https://www.ncbi.nlm.nih.gov/pubmed/25413472 http://dx.doi.org/10.1186/s12931-014-0146-6 |