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Optimized Generation of Functional Neutrophils and Macrophages from Patient-Specific Induced Pluripotent Stem Cells: Ex Vivo Models of X(0)-Linked, AR22(0)- and AR47(0)- Chronic Granulomatous Diseases

Chronic granulomatous disease (CGD) is an inherited orphan disorder caused by mutations in one of the five genes encoding reduced nicotinamide-adenine-dinucleotide-phosphate oxidase subunits, which subsequently lead to impairment in the production of microbicidal reactive oxygen species (ROS). In or...

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Detalles Bibliográficos
Autores principales:	Brault, Julie, Goutagny, Erwan, Telugu, Narasimha, Shao, Kaifeng, Baquié, Mathurin, Satre, Véronique, Coutton, Charles, Grunwald, Didier, Brion, Jean-Paul, Barlogis, Vincent, Stephan, Jean-Louis, Plantaz, Dominique, Hescheler, Jürgen, Krause, Karl-Heinz, Šarić, Tomo, Stasia, Marie José
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Mary Ann Liebert, Inc. 2014
Materias:	Original Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4245876/ https://www.ncbi.nlm.nih.gov/pubmed/25469316 http://dx.doi.org/10.1089/biores.2014.0045

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