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Hug1 is an intrinsically disordered protein that inhibits ribonucleotide reductase activity by directly binding Rnr2 subunit

Rad53 is a conserved protein kinase with a central role in DNA damage response and nucleotide metabolism. We observed that the expression of a dominant-lethal form of RAD53 leads to significant expression changes for at least 16 genes, including the RNR3 and the HUG1 genes, both of which are involve...

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Detalles Bibliográficos
Autores principales:	Meurisse, Julie, Bacquin, Agathe, Richet, Nicolas, Charbonnier, Jean-Baptiste, Ochsenbein, Françoise, Peyroche, Anne
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2014
Materias:	Genome Integrity, Repair and Replication
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4245953/ https://www.ncbi.nlm.nih.gov/pubmed/25378334 http://dx.doi.org/10.1093/nar/gku1095

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