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The conserved GTPase LepA contributes mainly to translation initiation in Escherichia coli

LepA is a paralog of EF-G found in all bacteria. Deletion of lepA confers no obvious growth defect in Escherichia coli, and the physiological role of LepA remains unknown. Here, we identify nine strains (ΔdksA, ΔmolR1, ΔrsgA, ΔtatB, ΔtonB, ΔtolR, ΔubiF, ΔubiG or ΔubiH) in which ΔlepA confers a synth...

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Detalles Bibliográficos
Autores principales: Balakrishnan, Rohan, Oman, Kenji, Shoji, Shinichiro, Bundschuh, Ralf, Fredrick, Kurt
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2014
Materias:
RNA
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4245954/
https://www.ncbi.nlm.nih.gov/pubmed/25378333
http://dx.doi.org/10.1093/nar/gku1098

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