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Amplicon rearrangements during the extrachromosomal and intrachromosomal amplification process in a glioma

The mechanisms of gene amplification in tumour cells are poorly understood and the relationship between extrachromosomal DNA molecules, named double minutes (dmins), and intrachromosomal homogeneously staining regions (hsr) is not documented at nucleotide resolution. Using fluorescent in situ hybrid...

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Detalles Bibliográficos
Autores principales:	Vogt, Nicolas, Gibaud, Anne, Lemoine, Frédéric, de la Grange, Pierre, Debatisse, Michelle, Malfoy, Bernard
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2014
Materias:	Genome Integrity, Repair and Replication
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4245956/ https://www.ncbi.nlm.nih.gov/pubmed/25378339 http://dx.doi.org/10.1093/nar/gku1101

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