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Crystal structure of a DNA/Ba(2+) G-quadruplex containing a water-mediated C-tetrad

We have determined the 1.50 Å crystal structure of the DNA decamer, d(CCA(CNV)KGCGTGG) ((CNV)K, 3-cyanovinylcarbazole), which forms a G-quadruplex structure in the presence of Ba(2+). The structure contains several unique features including a bulged nucleotide and the first crystal structure observa...

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Detalles Bibliográficos
Autores principales:	Zhang, Diana, Huang, Terry, Lukeman, Philip S., Paukstelis, Paul J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2014
Materias:	Structural Biology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4245957/ https://www.ncbi.nlm.nih.gov/pubmed/25389267 http://dx.doi.org/10.1093/nar/gku1122

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