Oxidative DNA damage is instrumental in hyperreplication stress-induced inviability of Escherichia coli

In Escherichia coli, an increase in the ATP bound form of the DnaA initiator protein results in hyperinitiation and inviability. Here, we show that such replication stress is tolerated during anaerobic growth. In hyperinitiating cells, a shift from anaerobic to aerobic growth resulted in appearance...

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Detalles Bibliográficos
Autores principales: Charbon, Godefroid, Bjørn, Louise, Mendoza-Chamizo, Belén, Frimodt-Møller, Jakob, Løbner-Olesen, Anders
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2014
Materias:
Genome Integrity, Repair and Replication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4245963/
https://www.ncbi.nlm.nih.gov/pubmed/25389264
http://dx.doi.org/10.1093/nar/gku1149

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4245963/
https://www.ncbi.nlm.nih.gov/pubmed/25389264
http://dx.doi.org/10.1093/nar/gku1149

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