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Oxidative DNA damage is instrumental in hyperreplication stress-induced inviability of Escherichia coli
In Escherichia coli, an increase in the ATP bound form of the DnaA initiator protein results in hyperinitiation and inviability. Here, we show that such replication stress is tolerated during anaerobic growth. In hyperinitiating cells, a shift from anaerobic to aerobic growth resulted in appearance...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2014
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4245963/ https://www.ncbi.nlm.nih.gov/pubmed/25389264 http://dx.doi.org/10.1093/nar/gku1149 |