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Before it crumbles: Fulminant Hepatic Failure secondary to Hodgkin's Lymphoma

Fulminant hepatic failure (FHF) is a relatively rare manifestation of Hodgkin's lymphoma. Clinical features, laboratory findings, and imaging of the liver are usually inconclusive, and liver biopsy may be required for confirmation. We present a case of an FHF in a woman 1 week after the diagnos...

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Autores principales: Karmacharya, Paras, Bhandari, Naresh, Aryal, Madan R., Pandit, Aashrayata A., Pathak, Ranjan, Ghimire, Sailu, Shrestha, Pragya, Bhatt, Vijaya R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Co-Action Publishing 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4246138/
https://www.ncbi.nlm.nih.gov/pubmed/25432655
http://dx.doi.org/10.3402/jchimp.v4.25821
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author Karmacharya, Paras
Bhandari, Naresh
Aryal, Madan R.
Pandit, Aashrayata A.
Pathak, Ranjan
Ghimire, Sailu
Shrestha, Pragya
Bhatt, Vijaya R.
author_facet Karmacharya, Paras
Bhandari, Naresh
Aryal, Madan R.
Pandit, Aashrayata A.
Pathak, Ranjan
Ghimire, Sailu
Shrestha, Pragya
Bhatt, Vijaya R.
author_sort Karmacharya, Paras
collection PubMed
description Fulminant hepatic failure (FHF) is a relatively rare manifestation of Hodgkin's lymphoma. Clinical features, laboratory findings, and imaging of the liver are usually inconclusive, and liver biopsy may be required for confirmation. We present a case of an FHF in a woman 1 week after the diagnosis of Hodgkin's lymphoma. Chemotherapy could not be instituted due to hepatic encephalopathy and other complications. Autopsy revealed diffuse infiltration of the liver parenchyma. This case illustrates the importance of early diagnosis and institution of chemotherapy, which may reverse the liver failure.
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spelling pubmed-42461382014-12-15 Before it crumbles: Fulminant Hepatic Failure secondary to Hodgkin's Lymphoma Karmacharya, Paras Bhandari, Naresh Aryal, Madan R. Pandit, Aashrayata A. Pathak, Ranjan Ghimire, Sailu Shrestha, Pragya Bhatt, Vijaya R. J Community Hosp Intern Med Perspect Case Report Fulminant hepatic failure (FHF) is a relatively rare manifestation of Hodgkin's lymphoma. Clinical features, laboratory findings, and imaging of the liver are usually inconclusive, and liver biopsy may be required for confirmation. We present a case of an FHF in a woman 1 week after the diagnosis of Hodgkin's lymphoma. Chemotherapy could not be instituted due to hepatic encephalopathy and other complications. Autopsy revealed diffuse infiltration of the liver parenchyma. This case illustrates the importance of early diagnosis and institution of chemotherapy, which may reverse the liver failure. Co-Action Publishing 2014-11-25 /pmc/articles/PMC4246138/ /pubmed/25432655 http://dx.doi.org/10.3402/jchimp.v4.25821 Text en © 2014 Paras Karmacharya et al. http://creativecommons.org/licenses/by-nc-nd/3.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution-Noncommercial 3.0 Unported License, permitting all non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Karmacharya, Paras
Bhandari, Naresh
Aryal, Madan R.
Pandit, Aashrayata A.
Pathak, Ranjan
Ghimire, Sailu
Shrestha, Pragya
Bhatt, Vijaya R.
Before it crumbles: Fulminant Hepatic Failure secondary to Hodgkin's Lymphoma
title Before it crumbles: Fulminant Hepatic Failure secondary to Hodgkin's Lymphoma
title_full Before it crumbles: Fulminant Hepatic Failure secondary to Hodgkin's Lymphoma
title_fullStr Before it crumbles: Fulminant Hepatic Failure secondary to Hodgkin's Lymphoma
title_full_unstemmed Before it crumbles: Fulminant Hepatic Failure secondary to Hodgkin's Lymphoma
title_short Before it crumbles: Fulminant Hepatic Failure secondary to Hodgkin's Lymphoma
title_sort before it crumbles: fulminant hepatic failure secondary to hodgkin's lymphoma
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4246138/
https://www.ncbi.nlm.nih.gov/pubmed/25432655
http://dx.doi.org/10.3402/jchimp.v4.25821
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