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Before it crumbles: Fulminant Hepatic Failure secondary to Hodgkin's Lymphoma
Fulminant hepatic failure (FHF) is a relatively rare manifestation of Hodgkin's lymphoma. Clinical features, laboratory findings, and imaging of the liver are usually inconclusive, and liver biopsy may be required for confirmation. We present a case of an FHF in a woman 1 week after the diagnos...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Co-Action Publishing
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4246138/ https://www.ncbi.nlm.nih.gov/pubmed/25432655 http://dx.doi.org/10.3402/jchimp.v4.25821 |
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author | Karmacharya, Paras Bhandari, Naresh Aryal, Madan R. Pandit, Aashrayata A. Pathak, Ranjan Ghimire, Sailu Shrestha, Pragya Bhatt, Vijaya R. |
author_facet | Karmacharya, Paras Bhandari, Naresh Aryal, Madan R. Pandit, Aashrayata A. Pathak, Ranjan Ghimire, Sailu Shrestha, Pragya Bhatt, Vijaya R. |
author_sort | Karmacharya, Paras |
collection | PubMed |
description | Fulminant hepatic failure (FHF) is a relatively rare manifestation of Hodgkin's lymphoma. Clinical features, laboratory findings, and imaging of the liver are usually inconclusive, and liver biopsy may be required for confirmation. We present a case of an FHF in a woman 1 week after the diagnosis of Hodgkin's lymphoma. Chemotherapy could not be instituted due to hepatic encephalopathy and other complications. Autopsy revealed diffuse infiltration of the liver parenchyma. This case illustrates the importance of early diagnosis and institution of chemotherapy, which may reverse the liver failure. |
format | Online Article Text |
id | pubmed-4246138 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2014 |
publisher | Co-Action Publishing |
record_format | MEDLINE/PubMed |
spelling | pubmed-42461382014-12-15 Before it crumbles: Fulminant Hepatic Failure secondary to Hodgkin's Lymphoma Karmacharya, Paras Bhandari, Naresh Aryal, Madan R. Pandit, Aashrayata A. Pathak, Ranjan Ghimire, Sailu Shrestha, Pragya Bhatt, Vijaya R. J Community Hosp Intern Med Perspect Case Report Fulminant hepatic failure (FHF) is a relatively rare manifestation of Hodgkin's lymphoma. Clinical features, laboratory findings, and imaging of the liver are usually inconclusive, and liver biopsy may be required for confirmation. We present a case of an FHF in a woman 1 week after the diagnosis of Hodgkin's lymphoma. Chemotherapy could not be instituted due to hepatic encephalopathy and other complications. Autopsy revealed diffuse infiltration of the liver parenchyma. This case illustrates the importance of early diagnosis and institution of chemotherapy, which may reverse the liver failure. Co-Action Publishing 2014-11-25 /pmc/articles/PMC4246138/ /pubmed/25432655 http://dx.doi.org/10.3402/jchimp.v4.25821 Text en © 2014 Paras Karmacharya et al. http://creativecommons.org/licenses/by-nc-nd/3.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution-Noncommercial 3.0 Unported License, permitting all non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Case Report Karmacharya, Paras Bhandari, Naresh Aryal, Madan R. Pandit, Aashrayata A. Pathak, Ranjan Ghimire, Sailu Shrestha, Pragya Bhatt, Vijaya R. Before it crumbles: Fulminant Hepatic Failure secondary to Hodgkin's Lymphoma |
title | Before it crumbles: Fulminant Hepatic Failure secondary to Hodgkin's Lymphoma |
title_full | Before it crumbles: Fulminant Hepatic Failure secondary to Hodgkin's Lymphoma |
title_fullStr | Before it crumbles: Fulminant Hepatic Failure secondary to Hodgkin's Lymphoma |
title_full_unstemmed | Before it crumbles: Fulminant Hepatic Failure secondary to Hodgkin's Lymphoma |
title_short | Before it crumbles: Fulminant Hepatic Failure secondary to Hodgkin's Lymphoma |
title_sort | before it crumbles: fulminant hepatic failure secondary to hodgkin's lymphoma |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4246138/ https://www.ncbi.nlm.nih.gov/pubmed/25432655 http://dx.doi.org/10.3402/jchimp.v4.25821 |
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