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Mixed adenocarcinoma and neuroendocrine prostate cancer: a case report

BACKGROUND: Neuroendocrine prostate cancer is rare but lethal. It is one of the most common extra pulmonary manifestations of small cell cancer. CASE PRESENTATION: Here we present a case report of a 53-year-old male who presents with a mixed adenocarcinoma and neuroendocrine prostate tumor on a back...

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Detalles Bibliográficos
Autores principales: Hingorani, Rittu, Young, Jessica, Alweis, Richard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Co-Action Publishing 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4246144/
https://www.ncbi.nlm.nih.gov/pubmed/25432647
http://dx.doi.org/10.3402/jchimp.v4.25176
Descripción
Sumario:BACKGROUND: Neuroendocrine prostate cancer is rare but lethal. It is one of the most common extra pulmonary manifestations of small cell cancer. CASE PRESENTATION: Here we present a case report of a 53-year-old male who presents with a mixed adenocarcinoma and neuroendocrine prostate tumor on a background of previously normal prostate-specific antigen (PSA). His initial symptoms prior to diagnosis included decreased urine output and acute kidney injury (AKI). CONCLUSION: Neuroendocrine tumor does not elevate the PSA level and hence is often a late finding with a poor prognosis. Special staining on histopathogy is required to reveal this diagnosis.