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The Effect of Chronic Bacterial Prostatitis on Semen Quality in Adult Men: A Meta-Analysis of Case-control Studies

Chronic bacterial prostatitis (CBP) is caused by bacterial infection and maintains a condition of lower urinary tract infection. It may be a cause of male infertility. However, studies showed inconsistent results regarding the effect of CBP on several parameters of semen. Hence, we conducted a meta-...

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Autores principales: Shang, Yonggang, Liu, Chengcheng, Cui, Dong, Han, Guangwei, Yi, Shanhong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4246207/
https://www.ncbi.nlm.nih.gov/pubmed/25429735
http://dx.doi.org/10.1038/srep07233
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author Shang, Yonggang
Liu, Chengcheng
Cui, Dong
Han, Guangwei
Yi, Shanhong
author_facet Shang, Yonggang
Liu, Chengcheng
Cui, Dong
Han, Guangwei
Yi, Shanhong
author_sort Shang, Yonggang
collection PubMed
description Chronic bacterial prostatitis (CBP) is caused by bacterial infection and maintains a condition of lower urinary tract infection. It may be a cause of male infertility. However, studies showed inconsistent results regarding the effect of CBP on several parameters of semen. Hence, we conducted a meta-analysis to examine the effect of CBP on basic semen parameters. A systematic review was conducted with Medline, PubMed, EMBASE, and two Chinese databases (CNKI and WANG FANG) to identify relevant studies that involved the effect of CBP on semen parameters up to July 2014. Both RevMan5.2 and STATA 12.0 software were used for the statistical analysis. Based on the inclusion and exclusion criteria, seven studies were included. The study illustrated that sperm vitality, sperm total motility, and the percentage of progressively motile sperm from CBP patients were significantly lower than controls (SMD(95%CI) −0.81[−1.14, −0.47], −1.00[−1.28, −0.73], −0.41 [−0.70, −0.12], P<0.05, respectively). However, CBP had no significant effect on semen volume, sperm concentration and the duration of semen liquefaction. In summary, our study revealed that there was a significant negative effect of CBP on sperm vitality, sperm total motility, and the percentage of progressively motile sperm. Additional, studies with larger number of subjects are needed.
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spelling pubmed-42462072014-12-05 The Effect of Chronic Bacterial Prostatitis on Semen Quality in Adult Men: A Meta-Analysis of Case-control Studies Shang, Yonggang Liu, Chengcheng Cui, Dong Han, Guangwei Yi, Shanhong Sci Rep Article Chronic bacterial prostatitis (CBP) is caused by bacterial infection and maintains a condition of lower urinary tract infection. It may be a cause of male infertility. However, studies showed inconsistent results regarding the effect of CBP on several parameters of semen. Hence, we conducted a meta-analysis to examine the effect of CBP on basic semen parameters. A systematic review was conducted with Medline, PubMed, EMBASE, and two Chinese databases (CNKI and WANG FANG) to identify relevant studies that involved the effect of CBP on semen parameters up to July 2014. Both RevMan5.2 and STATA 12.0 software were used for the statistical analysis. Based on the inclusion and exclusion criteria, seven studies were included. The study illustrated that sperm vitality, sperm total motility, and the percentage of progressively motile sperm from CBP patients were significantly lower than controls (SMD(95%CI) −0.81[−1.14, −0.47], −1.00[−1.28, −0.73], −0.41 [−0.70, −0.12], P<0.05, respectively). However, CBP had no significant effect on semen volume, sperm concentration and the duration of semen liquefaction. In summary, our study revealed that there was a significant negative effect of CBP on sperm vitality, sperm total motility, and the percentage of progressively motile sperm. Additional, studies with larger number of subjects are needed. Nature Publishing Group 2014-11-28 /pmc/articles/PMC4246207/ /pubmed/25429735 http://dx.doi.org/10.1038/srep07233 Text en Copyright © 2014, Macmillan Publishers Limited. All rights reserved http://creativecommons.org/licenses/by/4.0/ This work is licensed under a Creative Commons Attribution 4.0 International License. The images or other third party material in this article are included in the article's Creative Commons license, unless indicated otherwise in the credit line; if the material is not included under the Creative Commons license, users will need to obtain permission from the license holder in order to reproduce the material. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/
spellingShingle Article
Shang, Yonggang
Liu, Chengcheng
Cui, Dong
Han, Guangwei
Yi, Shanhong
The Effect of Chronic Bacterial Prostatitis on Semen Quality in Adult Men: A Meta-Analysis of Case-control Studies
title The Effect of Chronic Bacterial Prostatitis on Semen Quality in Adult Men: A Meta-Analysis of Case-control Studies
title_full The Effect of Chronic Bacterial Prostatitis on Semen Quality in Adult Men: A Meta-Analysis of Case-control Studies
title_fullStr The Effect of Chronic Bacterial Prostatitis on Semen Quality in Adult Men: A Meta-Analysis of Case-control Studies
title_full_unstemmed The Effect of Chronic Bacterial Prostatitis on Semen Quality in Adult Men: A Meta-Analysis of Case-control Studies
title_short The Effect of Chronic Bacterial Prostatitis on Semen Quality in Adult Men: A Meta-Analysis of Case-control Studies
title_sort effect of chronic bacterial prostatitis on semen quality in adult men: a meta-analysis of case-control studies
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4246207/
https://www.ncbi.nlm.nih.gov/pubmed/25429735
http://dx.doi.org/10.1038/srep07233
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