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Non-antibiotic quorum sensing inhibitors acting against N-acyl homoserine lactone synthase as druggable target
N-acylhomoserine lactone (AHL)-based quorum sensing (QS) is important for the regulation of proteobacterial virulence determinants. Thus, the inhibition of AHL synthases offers non-antibiotics-based therapeutic potentials against QS-mediated bacterial infections. In this work, functional AHL synthas...
Autores principales: | Chang, Chien-Yi, Krishnan, Thiba, Wang, Hao, Chen, Ye, Yin, Wai-Fong, Chong, Yee-Meng, Tan, Li Ying, Chong, Teik Min, Chan, Kok-Gan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4246208/ https://www.ncbi.nlm.nih.gov/pubmed/25430794 http://dx.doi.org/10.1038/srep07245 |
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