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A rare cause of hemoptysis
Angiosarcomas are rare, malignant, endothelial-cell tumors of vascular origin that can arise at any body site. They frequently metastasize to the lung, heralded by dyspnea, hemoptysis, chest pain, pneumothoraces, and diffuse pulmonary hemorrhage. However, in most cases lung metastases are discovered...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4246356/ https://www.ncbi.nlm.nih.gov/pubmed/26029560 http://dx.doi.org/10.1016/j.rmcr.2014.08.001 |
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author | Aversa, Meghan Bhinder, Sacha Tanguay, Jeffrey Thenganatt, John |
author_facet | Aversa, Meghan Bhinder, Sacha Tanguay, Jeffrey Thenganatt, John |
author_sort | Aversa, Meghan |
collection | PubMed |
description | Angiosarcomas are rare, malignant, endothelial-cell tumors of vascular origin that can arise at any body site. They frequently metastasize to the lung, heralded by dyspnea, hemoptysis, chest pain, pneumothoraces, and diffuse pulmonary hemorrhage. However, in most cases lung metastases are discovered after the diagnosis of a primary angiosarcoma has already been established. Very rarely will an undiagnosed metastatic angiosarcoma present as diffuse pulmonary hemorrhage. We describe the case of a 59-year-old male who presented to hospital with dyspnea and hemoptysis. CT chest revealed rapidly progressing nodular changes and broncho-alveolar lavage returns were progressively bloody. Open lung wedge biopsy ultimately revealed metastatic angiosarcoma and extensive pulmonary hemorrhage. Our case highlights the key clinical, radiological, and pathological features of this rare malignancy that frequently metastasizes to the lung and reminds clinicians to consider it as a cause of hemoptysis and pulmonary hemorrhage. |
format | Online Article Text |
id | pubmed-4246356 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2014 |
publisher | Elsevier |
record_format | MEDLINE/PubMed |
spelling | pubmed-42463562014-12-03 A rare cause of hemoptysis Aversa, Meghan Bhinder, Sacha Tanguay, Jeffrey Thenganatt, John Respir Med Case Rep Case Report Angiosarcomas are rare, malignant, endothelial-cell tumors of vascular origin that can arise at any body site. They frequently metastasize to the lung, heralded by dyspnea, hemoptysis, chest pain, pneumothoraces, and diffuse pulmonary hemorrhage. However, in most cases lung metastases are discovered after the diagnosis of a primary angiosarcoma has already been established. Very rarely will an undiagnosed metastatic angiosarcoma present as diffuse pulmonary hemorrhage. We describe the case of a 59-year-old male who presented to hospital with dyspnea and hemoptysis. CT chest revealed rapidly progressing nodular changes and broncho-alveolar lavage returns were progressively bloody. Open lung wedge biopsy ultimately revealed metastatic angiosarcoma and extensive pulmonary hemorrhage. Our case highlights the key clinical, radiological, and pathological features of this rare malignancy that frequently metastasizes to the lung and reminds clinicians to consider it as a cause of hemoptysis and pulmonary hemorrhage. Elsevier 2014-09-28 /pmc/articles/PMC4246356/ /pubmed/26029560 http://dx.doi.org/10.1016/j.rmcr.2014.08.001 Text en © 2014 The Authors http://creativecommons.org/licenses/by-nc-nd/3.0/ This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/3.0/). |
spellingShingle | Case Report Aversa, Meghan Bhinder, Sacha Tanguay, Jeffrey Thenganatt, John A rare cause of hemoptysis |
title | A rare cause of hemoptysis |
title_full | A rare cause of hemoptysis |
title_fullStr | A rare cause of hemoptysis |
title_full_unstemmed | A rare cause of hemoptysis |
title_short | A rare cause of hemoptysis |
title_sort | rare cause of hemoptysis |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4246356/ https://www.ncbi.nlm.nih.gov/pubmed/26029560 http://dx.doi.org/10.1016/j.rmcr.2014.08.001 |
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