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A rare cause of hemoptysis

Angiosarcomas are rare, malignant, endothelial-cell tumors of vascular origin that can arise at any body site. They frequently metastasize to the lung, heralded by dyspnea, hemoptysis, chest pain, pneumothoraces, and diffuse pulmonary hemorrhage. However, in most cases lung metastases are discovered...

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Detalles Bibliográficos
Autores principales: Aversa, Meghan, Bhinder, Sacha, Tanguay, Jeffrey, Thenganatt, John
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4246356/
https://www.ncbi.nlm.nih.gov/pubmed/26029560
http://dx.doi.org/10.1016/j.rmcr.2014.08.001
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author Aversa, Meghan
Bhinder, Sacha
Tanguay, Jeffrey
Thenganatt, John
author_facet Aversa, Meghan
Bhinder, Sacha
Tanguay, Jeffrey
Thenganatt, John
author_sort Aversa, Meghan
collection PubMed
description Angiosarcomas are rare, malignant, endothelial-cell tumors of vascular origin that can arise at any body site. They frequently metastasize to the lung, heralded by dyspnea, hemoptysis, chest pain, pneumothoraces, and diffuse pulmonary hemorrhage. However, in most cases lung metastases are discovered after the diagnosis of a primary angiosarcoma has already been established. Very rarely will an undiagnosed metastatic angiosarcoma present as diffuse pulmonary hemorrhage. We describe the case of a 59-year-old male who presented to hospital with dyspnea and hemoptysis. CT chest revealed rapidly progressing nodular changes and broncho-alveolar lavage returns were progressively bloody. Open lung wedge biopsy ultimately revealed metastatic angiosarcoma and extensive pulmonary hemorrhage. Our case highlights the key clinical, radiological, and pathological features of this rare malignancy that frequently metastasizes to the lung and reminds clinicians to consider it as a cause of hemoptysis and pulmonary hemorrhage.
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spelling pubmed-42463562014-12-03 A rare cause of hemoptysis Aversa, Meghan Bhinder, Sacha Tanguay, Jeffrey Thenganatt, John Respir Med Case Rep Case Report Angiosarcomas are rare, malignant, endothelial-cell tumors of vascular origin that can arise at any body site. They frequently metastasize to the lung, heralded by dyspnea, hemoptysis, chest pain, pneumothoraces, and diffuse pulmonary hemorrhage. However, in most cases lung metastases are discovered after the diagnosis of a primary angiosarcoma has already been established. Very rarely will an undiagnosed metastatic angiosarcoma present as diffuse pulmonary hemorrhage. We describe the case of a 59-year-old male who presented to hospital with dyspnea and hemoptysis. CT chest revealed rapidly progressing nodular changes and broncho-alveolar lavage returns were progressively bloody. Open lung wedge biopsy ultimately revealed metastatic angiosarcoma and extensive pulmonary hemorrhage. Our case highlights the key clinical, radiological, and pathological features of this rare malignancy that frequently metastasizes to the lung and reminds clinicians to consider it as a cause of hemoptysis and pulmonary hemorrhage. Elsevier 2014-09-28 /pmc/articles/PMC4246356/ /pubmed/26029560 http://dx.doi.org/10.1016/j.rmcr.2014.08.001 Text en © 2014 The Authors http://creativecommons.org/licenses/by-nc-nd/3.0/ This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/3.0/).
spellingShingle Case Report
Aversa, Meghan
Bhinder, Sacha
Tanguay, Jeffrey
Thenganatt, John
A rare cause of hemoptysis
title A rare cause of hemoptysis
title_full A rare cause of hemoptysis
title_fullStr A rare cause of hemoptysis
title_full_unstemmed A rare cause of hemoptysis
title_short A rare cause of hemoptysis
title_sort rare cause of hemoptysis
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4246356/
https://www.ncbi.nlm.nih.gov/pubmed/26029560
http://dx.doi.org/10.1016/j.rmcr.2014.08.001
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