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Idiopathic CD4 lymphocytopenia with giant cell arteritis and pulmonary mucormycosis
Idiopathic CD4 lymphocytopenia (ICL) is characterized by a low CD4+ lymphocyte count in the absence of HIV or other underlying etiologies. We report a case of a 57-year old man with ICL and giant cell arteritis (GCA) who developed pulmonary mucormycosis, which, to our knowledge, is the first report...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4246401/ https://www.ncbi.nlm.nih.gov/pubmed/25473601 http://dx.doi.org/10.1016/j.mmcr.2014.10.002 |
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author | Denu, Ryan A. Rush, Patrick S. Ahrens, Sarah E. Westergaard, Ryan P. |
author_facet | Denu, Ryan A. Rush, Patrick S. Ahrens, Sarah E. Westergaard, Ryan P. |
author_sort | Denu, Ryan A. |
collection | PubMed |
description | Idiopathic CD4 lymphocytopenia (ICL) is characterized by a low CD4+ lymphocyte count in the absence of HIV or other underlying etiologies. We report a case of a 57-year old man with ICL and giant cell arteritis (GCA) who developed pulmonary mucormycosis, which, to our knowledge, is the first report of these occurring in a patient with ICL. Abnormally low total lymphocyte or CD4+ cell counts occurring in patients with autoimmune disorders should alert clinicians to the possibility of ICL. Immunosuppressive treatment should be used with caution in this context. |
format | Online Article Text |
id | pubmed-4246401 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2014 |
publisher | Elsevier |
record_format | MEDLINE/PubMed |
spelling | pubmed-42464012014-12-03 Idiopathic CD4 lymphocytopenia with giant cell arteritis and pulmonary mucormycosis Denu, Ryan A. Rush, Patrick S. Ahrens, Sarah E. Westergaard, Ryan P. Med Mycol Case Rep Article Idiopathic CD4 lymphocytopenia (ICL) is characterized by a low CD4+ lymphocyte count in the absence of HIV or other underlying etiologies. We report a case of a 57-year old man with ICL and giant cell arteritis (GCA) who developed pulmonary mucormycosis, which, to our knowledge, is the first report of these occurring in a patient with ICL. Abnormally low total lymphocyte or CD4+ cell counts occurring in patients with autoimmune disorders should alert clinicians to the possibility of ICL. Immunosuppressive treatment should be used with caution in this context. Elsevier 2014-11-04 /pmc/articles/PMC4246401/ /pubmed/25473601 http://dx.doi.org/10.1016/j.mmcr.2014.10.002 Text en © 2014 The Authors http://creativecommons.org/licenses/by-nc-nd/3.0/ This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/3.0/). |
spellingShingle | Article Denu, Ryan A. Rush, Patrick S. Ahrens, Sarah E. Westergaard, Ryan P. Idiopathic CD4 lymphocytopenia with giant cell arteritis and pulmonary mucormycosis |
title | Idiopathic CD4 lymphocytopenia with giant cell arteritis and pulmonary mucormycosis |
title_full | Idiopathic CD4 lymphocytopenia with giant cell arteritis and pulmonary mucormycosis |
title_fullStr | Idiopathic CD4 lymphocytopenia with giant cell arteritis and pulmonary mucormycosis |
title_full_unstemmed | Idiopathic CD4 lymphocytopenia with giant cell arteritis and pulmonary mucormycosis |
title_short | Idiopathic CD4 lymphocytopenia with giant cell arteritis and pulmonary mucormycosis |
title_sort | idiopathic cd4 lymphocytopenia with giant cell arteritis and pulmonary mucormycosis |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4246401/ https://www.ncbi.nlm.nih.gov/pubmed/25473601 http://dx.doi.org/10.1016/j.mmcr.2014.10.002 |
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