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Idiopathic CD4 lymphocytopenia with giant cell arteritis and pulmonary mucormycosis

Idiopathic CD4 lymphocytopenia (ICL) is characterized by a low CD4+ lymphocyte count in the absence of HIV or other underlying etiologies. We report a case of a 57-year old man with ICL and giant cell arteritis (GCA) who developed pulmonary mucormycosis, which, to our knowledge, is the first report...

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Autores principales: Denu, Ryan A., Rush, Patrick S., Ahrens, Sarah E., Westergaard, Ryan P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4246401/
https://www.ncbi.nlm.nih.gov/pubmed/25473601
http://dx.doi.org/10.1016/j.mmcr.2014.10.002
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author Denu, Ryan A.
Rush, Patrick S.
Ahrens, Sarah E.
Westergaard, Ryan P.
author_facet Denu, Ryan A.
Rush, Patrick S.
Ahrens, Sarah E.
Westergaard, Ryan P.
author_sort Denu, Ryan A.
collection PubMed
description Idiopathic CD4 lymphocytopenia (ICL) is characterized by a low CD4+ lymphocyte count in the absence of HIV or other underlying etiologies. We report a case of a 57-year old man with ICL and giant cell arteritis (GCA) who developed pulmonary mucormycosis, which, to our knowledge, is the first report of these occurring in a patient with ICL. Abnormally low total lymphocyte or CD4+ cell counts occurring in patients with autoimmune disorders should alert clinicians to the possibility of ICL. Immunosuppressive treatment should be used with caution in this context.
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spelling pubmed-42464012014-12-03 Idiopathic CD4 lymphocytopenia with giant cell arteritis and pulmonary mucormycosis Denu, Ryan A. Rush, Patrick S. Ahrens, Sarah E. Westergaard, Ryan P. Med Mycol Case Rep Article Idiopathic CD4 lymphocytopenia (ICL) is characterized by a low CD4+ lymphocyte count in the absence of HIV or other underlying etiologies. We report a case of a 57-year old man with ICL and giant cell arteritis (GCA) who developed pulmonary mucormycosis, which, to our knowledge, is the first report of these occurring in a patient with ICL. Abnormally low total lymphocyte or CD4+ cell counts occurring in patients with autoimmune disorders should alert clinicians to the possibility of ICL. Immunosuppressive treatment should be used with caution in this context. Elsevier 2014-11-04 /pmc/articles/PMC4246401/ /pubmed/25473601 http://dx.doi.org/10.1016/j.mmcr.2014.10.002 Text en © 2014 The Authors http://creativecommons.org/licenses/by-nc-nd/3.0/ This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/3.0/).
spellingShingle Article
Denu, Ryan A.
Rush, Patrick S.
Ahrens, Sarah E.
Westergaard, Ryan P.
Idiopathic CD4 lymphocytopenia with giant cell arteritis and pulmonary mucormycosis
title Idiopathic CD4 lymphocytopenia with giant cell arteritis and pulmonary mucormycosis
title_full Idiopathic CD4 lymphocytopenia with giant cell arteritis and pulmonary mucormycosis
title_fullStr Idiopathic CD4 lymphocytopenia with giant cell arteritis and pulmonary mucormycosis
title_full_unstemmed Idiopathic CD4 lymphocytopenia with giant cell arteritis and pulmonary mucormycosis
title_short Idiopathic CD4 lymphocytopenia with giant cell arteritis and pulmonary mucormycosis
title_sort idiopathic cd4 lymphocytopenia with giant cell arteritis and pulmonary mucormycosis
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4246401/
https://www.ncbi.nlm.nih.gov/pubmed/25473601
http://dx.doi.org/10.1016/j.mmcr.2014.10.002
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