Cargando…
Functional principal component analysis as a new methodology for the analysis of the impact of two rehabilitation protocols in functional recovery after stroke
BACKGROUND: This study addressed the problem of evaluating the effectiveness of two protocols of physiotherapy for functional recovery after stroke. In particular, the study explored the use of Functional Principal Component Analysis (FPCA), a multivariate data analysis in order to assess and clarif...
Autores principales: | , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2014
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4246446/ https://www.ncbi.nlm.nih.gov/pubmed/25208616 http://dx.doi.org/10.1186/1743-0003-11-134 |
_version_ | 1782346515412418560 |
---|---|
author | Sánchez-Sánchez, M Luz Belda-Lois, Juan-Manuel Mena-del Horno, Silvia Viosca-Herrero, Enrique Gisbert-Morant, Beatriz Igual-Camacho, Celedonia Bermejo-Bosch, Ignacio |
author_facet | Sánchez-Sánchez, M Luz Belda-Lois, Juan-Manuel Mena-del Horno, Silvia Viosca-Herrero, Enrique Gisbert-Morant, Beatriz Igual-Camacho, Celedonia Bermejo-Bosch, Ignacio |
author_sort | Sánchez-Sánchez, M Luz |
collection | PubMed |
description | BACKGROUND: This study addressed the problem of evaluating the effectiveness of two protocols of physiotherapy for functional recovery after stroke. In particular, the study explored the use of Functional Principal Component Analysis (FPCA), a multivariate data analysis in order to assess and clarify the process of regaining independence after stroke. METHODS: A randomized double-blind controlled trial was performed. Thirteen subjects with residual hemiparesis after a single stroke episode were measured in both in- and outpatient settings at a district hospital. All subjects were able to walk before suffering the stroke and were hemodynamically stable within the first week after stroke. Control and target groups were treated with conventional physiotherapy for stroke, but specific techniques were added for treatment of the target group depending on patients’ functional levels. Independence level was assessed with the Barthel Index (BI) throughout 7 evolution stages (hemodynamic stability, beginning of standing, beginning of physical therapy sessions in the physiotherapy ward and monthly assessment for 6 months after stroke). RESULTS: FPCA was applied for data analysis. Statistically significant differences were found in the dynamics of the recovery process between the two physiotherapy protocols. The target group showed a trend of improvement six months after stroke that was not present in the control group. CONCLUSIONS: FPCA is a method which may be used to provide greater insight into the analysis of the rehabilitation process than that provided by conventional parametric methods. So, by using the whole curves as basic data parameters, subtle differences in the rehabilitation process can be found. FPCA represents a future aid for the fine analysis of similar physiotherapy techniques, when applied in subjects with a huge variability of functional recovery, as in the case of post-stroke patients. ELECTRONIC SUPPLEMENTARY MATERIAL: The online version of this article (doi:10.1186/1743-0003-11-134) contains supplementary material, which is available to authorized users. |
format | Online Article Text |
id | pubmed-4246446 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2014 |
publisher | BioMed Central |
record_format | MEDLINE/PubMed |
spelling | pubmed-42464462014-11-29 Functional principal component analysis as a new methodology for the analysis of the impact of two rehabilitation protocols in functional recovery after stroke Sánchez-Sánchez, M Luz Belda-Lois, Juan-Manuel Mena-del Horno, Silvia Viosca-Herrero, Enrique Gisbert-Morant, Beatriz Igual-Camacho, Celedonia Bermejo-Bosch, Ignacio J Neuroeng Rehabil Methodology BACKGROUND: This study addressed the problem of evaluating the effectiveness of two protocols of physiotherapy for functional recovery after stroke. In particular, the study explored the use of Functional Principal Component Analysis (FPCA), a multivariate data analysis in order to assess and clarify the process of regaining independence after stroke. METHODS: A randomized double-blind controlled trial was performed. Thirteen subjects with residual hemiparesis after a single stroke episode were measured in both in- and outpatient settings at a district hospital. All subjects were able to walk before suffering the stroke and were hemodynamically stable within the first week after stroke. Control and target groups were treated with conventional physiotherapy for stroke, but specific techniques were added for treatment of the target group depending on patients’ functional levels. Independence level was assessed with the Barthel Index (BI) throughout 7 evolution stages (hemodynamic stability, beginning of standing, beginning of physical therapy sessions in the physiotherapy ward and monthly assessment for 6 months after stroke). RESULTS: FPCA was applied for data analysis. Statistically significant differences were found in the dynamics of the recovery process between the two physiotherapy protocols. The target group showed a trend of improvement six months after stroke that was not present in the control group. CONCLUSIONS: FPCA is a method which may be used to provide greater insight into the analysis of the rehabilitation process than that provided by conventional parametric methods. So, by using the whole curves as basic data parameters, subtle differences in the rehabilitation process can be found. FPCA represents a future aid for the fine analysis of similar physiotherapy techniques, when applied in subjects with a huge variability of functional recovery, as in the case of post-stroke patients. ELECTRONIC SUPPLEMENTARY MATERIAL: The online version of this article (doi:10.1186/1743-0003-11-134) contains supplementary material, which is available to authorized users. BioMed Central 2014-09-10 /pmc/articles/PMC4246446/ /pubmed/25208616 http://dx.doi.org/10.1186/1743-0003-11-134 Text en © Sánchez-Sánchez et al.; licensee BioMed Central Ltd. 2014 This article is published under license to BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated. |
spellingShingle | Methodology Sánchez-Sánchez, M Luz Belda-Lois, Juan-Manuel Mena-del Horno, Silvia Viosca-Herrero, Enrique Gisbert-Morant, Beatriz Igual-Camacho, Celedonia Bermejo-Bosch, Ignacio Functional principal component analysis as a new methodology for the analysis of the impact of two rehabilitation protocols in functional recovery after stroke |
title | Functional principal component analysis as a new methodology for the analysis of the impact of two rehabilitation protocols in functional recovery after stroke |
title_full | Functional principal component analysis as a new methodology for the analysis of the impact of two rehabilitation protocols in functional recovery after stroke |
title_fullStr | Functional principal component analysis as a new methodology for the analysis of the impact of two rehabilitation protocols in functional recovery after stroke |
title_full_unstemmed | Functional principal component analysis as a new methodology for the analysis of the impact of two rehabilitation protocols in functional recovery after stroke |
title_short | Functional principal component analysis as a new methodology for the analysis of the impact of two rehabilitation protocols in functional recovery after stroke |
title_sort | functional principal component analysis as a new methodology for the analysis of the impact of two rehabilitation protocols in functional recovery after stroke |
topic | Methodology |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4246446/ https://www.ncbi.nlm.nih.gov/pubmed/25208616 http://dx.doi.org/10.1186/1743-0003-11-134 |
work_keys_str_mv | AT sanchezsanchezmluz functionalprincipalcomponentanalysisasanewmethodologyfortheanalysisoftheimpactoftworehabilitationprotocolsinfunctionalrecoveryafterstroke AT beldaloisjuanmanuel functionalprincipalcomponentanalysisasanewmethodologyfortheanalysisoftheimpactoftworehabilitationprotocolsinfunctionalrecoveryafterstroke AT menadelhornosilvia functionalprincipalcomponentanalysisasanewmethodologyfortheanalysisoftheimpactoftworehabilitationprotocolsinfunctionalrecoveryafterstroke AT vioscaherreroenrique functionalprincipalcomponentanalysisasanewmethodologyfortheanalysisoftheimpactoftworehabilitationprotocolsinfunctionalrecoveryafterstroke AT gisbertmorantbeatriz functionalprincipalcomponentanalysisasanewmethodologyfortheanalysisoftheimpactoftworehabilitationprotocolsinfunctionalrecoveryafterstroke AT igualcamachoceledonia functionalprincipalcomponentanalysisasanewmethodologyfortheanalysisoftheimpactoftworehabilitationprotocolsinfunctionalrecoveryafterstroke AT bermejoboschignacio functionalprincipalcomponentanalysisasanewmethodologyfortheanalysisoftheimpactoftworehabilitationprotocolsinfunctionalrecoveryafterstroke |