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Acute insulin resistance stimulates and insulin sensitization attenuates vascular smooth muscle cell migration and proliferation

Differential activation/deactivation of insulin signaling, PI‐3K and MAP‐K pathways by high glucose and palmitate, with/out the insulin sensitizer pioglitazone (PIO), have been previously shown in vascular smooth muscle cells (VSMCs). To determine the biological impact of these molecular changes, we...

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Detalles Bibliográficos
Autores principales: Cersosimo, Eugenio, Xu, Xiaojing, Upala, Sikarin, Triplitt, Curtis, Musi, Nicolas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wiley Periodicals, Inc. 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4246575/
https://www.ncbi.nlm.nih.gov/pubmed/25138792
http://dx.doi.org/10.14814/phy2.12123