Acute and chronic systemic CB(1) cannabinoid receptor blockade improves blood pressure regulation and metabolic profile in hypertensive (mRen2)27 rats

We investigated acute and chronic effects of CB(1) cannabinoid receptor blockade in renin‐angiotensin system‐dependent hypertension using rimonabant (SR141716A), an orally active antagonist with central and peripheral actions. In transgenic (mRen2)27 rats, a model of angiotensin II‐dependent hyperte...

Descripción completa

Detalles Bibliográficos
Autores principales: Schaich, Chris L., Shaltout, Hossam A., Brosnihan, K. Bridget, Howlett, Allyn C., Diz, Debra I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wiley Periodicals, Inc. 2014
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4246581/
https://www.ncbi.nlm.nih.gov/pubmed/25168868
http://dx.doi.org/10.14814/phy2.12108

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4246581/
https://www.ncbi.nlm.nih.gov/pubmed/25168868
http://dx.doi.org/10.14814/phy2.12108

Ejemplares similares