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Acute and chronic systemic CB(1) cannabinoid receptor blockade improves blood pressure regulation and metabolic profile in hypertensive (mRen2)27 rats
We investigated acute and chronic effects of CB(1) cannabinoid receptor blockade in renin‐angiotensin system‐dependent hypertension using rimonabant (SR141716A), an orally active antagonist with central and peripheral actions. In transgenic (mRen2)27 rats, a model of angiotensin II‐dependent hyperte...
Autores principales: | Schaich, Chris L., Shaltout, Hossam A., Brosnihan, K. Bridget, Howlett, Allyn C., Diz, Debra I. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Wiley Periodicals, Inc.
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4246581/ https://www.ncbi.nlm.nih.gov/pubmed/25168868 http://dx.doi.org/10.14814/phy2.12108 |
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