Folliculin regulates cell–cell adhesion, AMPK, and mTORC1 in a cell‐type‐specific manner in lung‐derived cells

Germline loss‐of‐function BHD mutations cause cystic lung disease and hereditary pneumothorax, yet little is known about the impact of BHD mutations in the lung. Folliculin (FLCN), the product of the Birt–Hogg–Dube (BHD) gene, has been linked to altered cell–cell adhesion and to the AMPK and mTORC1...

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Detalles Bibliográficos
Autores principales: Khabibullin, Damir, Medvetz, Douglas A., Pinilla, Miguel, Hariharan, Venkatesh, Li, Chenggang, Hergrueter, Anja, Laucho Contreras, Maria, Zhang, Erik, Parkhitko, Andrey, Yu, Jane J., Owen, Caroline A., Huang, Hayden, Baron, Rebecca M., Henske, Elizabeth P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wiley Periodicals, Inc. 2014
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4246594/
https://www.ncbi.nlm.nih.gov/pubmed/25121506
http://dx.doi.org/10.14814/phy2.12107

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