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Methylation analysis of the DAPK1 gene in imatinib-resistant chronic myeloid leukemia patients

Death-associated protein kinase-1 (DAPK1) is a pro-apoptotic gene that induces cellular apoptosis in response to internal and external apoptotic stimulants. The silencing of DAPK1 can result in uncontrolled cell proliferation, indicating that it may have a role in tumor suppression. DAPK1 activity c...

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Detalles Bibliográficos
Autores principales: CELIK, SELCEN, AKCORA, DILARA, OZKAN, TULIN, VAROL, NURAY, AYDOS, SENA, SUNGUROGLU, ASUMAN
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4246661/
https://www.ncbi.nlm.nih.gov/pubmed/25435999
http://dx.doi.org/10.3892/ol.2014.2677