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Biological redundancy of endogenous GPCR ligands in the gut and the potential for endogenous functional selectivity

This review focuses on the existence and function of multiple endogenous agonists of the somatostatin and opioid receptors with an emphasis on their expression in the gastrointestinal tract. These agonists generally arise from the proteolytic cleavage of prepropeptides during peptide maturation or f...

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Detalles Bibliográficos
Autores principales: Thompson, Georgina L., Canals, Meritxell, Poole, Daniel P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4246669/
https://www.ncbi.nlm.nih.gov/pubmed/25506328
http://dx.doi.org/10.3389/fphar.2014.00262

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