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Enhanced antifungal effects of amphotericin B-TPGS-b-(PCL-ran-PGA) nanoparticles in vitro and in vivo

BACKGROUND: Amphotericin B (AMB) is a polyene antibiotic with broad spectrum antifungal activity, but its clinical toxicities and poor solubility limit the wide application of AMB in clinical practice. Recently, new drug-loaded nanoparticles (NPs) – diblock copolymer D-α-tocopheryl polyethylene glyc...

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Detalles Bibliográficos
Autores principales:	Tang, Xiaolong, Zhu, He, Sun, Ledong, Hou, Wei, Cai, Shuyu, Zhang, Rongbo, Liu, Feng
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove Medical Press 2014
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4247144/ https://www.ncbi.nlm.nih.gov/pubmed/25473279 http://dx.doi.org/10.2147/IJN.S71623

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