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Anti-inflammatory effects of Edaravone and Scutellarin in activated microglia in experimentally induced ischemia injury in rats and in BV-2 microglia

BACKGROUND: In response to cerebral ischemia, activated microglia release excessive inflammatory mediators which contribute to neuronal damage. Therefore, inhibition of microglial over-activation could be a therapeutic strategy to alleviate various microglia-mediated neuroinflammation. This study wa...

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Detalles Bibliográficos
Autores principales: Yuan, Yun, Zha, Hao, Rangarajan, Parakalan, Ling, Eng-Ang, Wu, Chunyun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4247200/
https://www.ncbi.nlm.nih.gov/pubmed/25416145
http://dx.doi.org/10.1186/s12868-014-0125-3