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PhTX-II a Basic Myotoxic Phospholipase A(2) from Porthidium hyoprora Snake Venom, Pharmacological Characterization and Amino Acid Sequence by Mass Spectrometry
A monomeric basic PLA(2) (PhTX-II) of 14149.08 Da molecular weight was purified to homogeneity from Porthidium hyoprora venom. Amino acid sequence by in tandem mass spectrometry revealed that PhTX-II belongs to Asp49 PLA(2) enzyme class and displays conserved domains as the catalytic network, Ca(2+)...
Autores principales: | Huancahuire-Vega, Salomón, Ponce-Soto, Luis Alberto, Marangoni, Sergio |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4247251/ https://www.ncbi.nlm.nih.gov/pubmed/25365526 http://dx.doi.org/10.3390/toxins6113077 |
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