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Analysis of microRNA transcription and post-transcriptional processing by Dicer in the context of CHO cell proliferation

CHO cells are the mammalian cell line of choice for recombinant production of therapeutic proteins. However, their low rate of proliferation limits obtainable space-time yields due to inefficient biomass accumulation. We set out to correlate microRNA transcription to cell-specific growth-rate by mic...

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Detalles Bibliográficos
Autores principales:	Hackl, Matthias, Jadhav, Vaibhav, Klanert, Gerald, Karbiener, Michael, Scheideler, Marcel, Grillari, Johannes, Borth, Nicole
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier Science Publishers 2014
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4247382/ https://www.ncbi.nlm.nih.gov/pubmed/24486028 http://dx.doi.org/10.1016/j.jbiotec.2013.12.018

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