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The effect of calorie restriction on insulin signaling in skeletal muscle and adipose tissue of Ames dwarf mice
Long-living Ames dwarf (df/df) mice are homozygous for a mutation of the Prop1(df) gene. As a result, mice are deficient in growth hormone (GH), prolactin (PRL) and thyrotropin (TSH). In spite of the hormonal deficiencies, df/df mice live significantly longer and healthier lives compared to their wi...
Autores principales: | Wiesenborn, Denise S., Menon, Vinal, Zhi, Xu, Do, Andrew, Gesing, Adam, Wang, Zhihui, Bartke, Andrzej, Altomare, Deborah A., Masternak, Michal M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4247389/ https://www.ncbi.nlm.nih.gov/pubmed/25411241 |
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