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HDAC and HAT inhibitors differently affect analgesia mediated by group II metabotropic glutamate receptors

BACKGROUND: Histone deacetylases (HDACs) and histone acetyltransferases (HATs) are key players in epigenetic regulation of gene expression. Analgesic activity by HDAC inhibitors has been reported in different pain models including inflammatory and neuropathic pain. These drugs interfere with gene ex...

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Detalles Bibliográficos
Autores principales:	Zammataro, Magda, Sortino, Maria Angela, Parenti, Carmela, Gereau, Robert W, Chiechio, Santina
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2014
Materias:	Short Report
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4247606/ https://www.ncbi.nlm.nih.gov/pubmed/25406541 http://dx.doi.org/10.1186/1744-8069-10-68

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