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The burden of nosocomial staphylococcus aureus bloodstream infection in South Korea: a prospective hospital-based nationwide study
BACKGROUND: We estimated the nationwide burden of nosocomial S. aureus bloodstream infection (SA-BSI), a major cause of nosocomial infection, in South Korea. METHODS: To evaluate the nationwide incidence of nosocomial SA-BSI, cases of SA-BSI were prospectively collected from 22 hospitals with over 5...
Autores principales: | , , , , , , , , , , , , , , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4247623/ https://www.ncbi.nlm.nih.gov/pubmed/25891200 http://dx.doi.org/10.1186/s12879-014-0590-4 |
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author | Kim, Chung-Jong Kim, Hong-Bin Oh, Myoung-don Kim, Yunhee Kim, Arim Oh, Sung-Hee Song, Kyoung-Ho Kim, Eu Suk Cho, Yong Kyun Choi, Young Hwa Park, Jinyong Kim, Baek-Nam Kim, Nam-Joong Kim, Kye-Hyung Lee, Eun Jung Jun, Jae-Bum Kim, Young Keun Kiem, Sung min Choi, Hee Jung Choo, Eun Ju Sohn, Kyung-mok Lee, Shinwon Chang, Hyun Ha Bang, Ji Hwan Lee, Su Jin Lee, Jae Hoon Park, Seong Yeon Jeon, Min Hyok Yun, Na Ra |
author_facet | Kim, Chung-Jong Kim, Hong-Bin Oh, Myoung-don Kim, Yunhee Kim, Arim Oh, Sung-Hee Song, Kyoung-Ho Kim, Eu Suk Cho, Yong Kyun Choi, Young Hwa Park, Jinyong Kim, Baek-Nam Kim, Nam-Joong Kim, Kye-Hyung Lee, Eun Jung Jun, Jae-Bum Kim, Young Keun Kiem, Sung min Choi, Hee Jung Choo, Eun Ju Sohn, Kyung-mok Lee, Shinwon Chang, Hyun Ha Bang, Ji Hwan Lee, Su Jin Lee, Jae Hoon Park, Seong Yeon Jeon, Min Hyok Yun, Na Ra |
author_sort | Kim, Chung-Jong |
collection | PubMed |
description | BACKGROUND: We estimated the nationwide burden of nosocomial S. aureus bloodstream infection (SA-BSI), a major cause of nosocomial infection, in South Korea. METHODS: To evaluate the nationwide incidence of nosocomial SA-BSI, cases of SA-BSI were prospectively collected from 22 hospitals with over 500 beds over 4?months. Data on patient-days were obtained from a national health insurance database containing the claims data for all healthcare facilities in South Korea. The additional cost of SA-BSI was estimated through a matched case?control study. The economic burden was calculated from the sum of the medical costs, the costs of caregiving and loss of productivity. RESULTS: Three hundred and thirty nine cases of nosocomial SA-BSI were included in the study: 254 cases of methicillin-resistant SA-BSI (MRSA-BSI) and 85 cases of methicillin-susceptible SA-BSI (MSSA-BSI). Death related to BSI occurred in 81 cases (31.9%) of MRSA-BSI and 12 cases (14.1%) of MSSA-BSI. The estimated incidence of nosocomial MRSA-BSI was 0.12/1,000 patient-days and that of nosocomial MSSA-BSI, 0.04/1,000 patient-days. The estimated annual cases of nosocomial BSI were 2,946 for MRSA and 986 for MSSA in South Korea. The additional economic burden per case of nosocomial SA-BSI was US $20,494 for MRSA-BSI and $6,914 for MSSA-BSI. Total additional annual cost of nosocomial SA-BSI was $67,192,559. CONCLUSION: In view of the burden of nosocomial SA-BSI, a national strategy for reducing nosocomial SA-BSI is urgently needed in South Korea. ELECTRONIC SUPPLEMENTARY MATERIAL: The online version of this article (doi:10.1186/s12879-014-0590-4) contains supplementary material, which is available to authorized users. |
format | Online Article Text |
id | pubmed-4247623 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2014 |
publisher | BioMed Central |
record_format | MEDLINE/PubMed |
spelling | pubmed-42476232014-11-30 The burden of nosocomial staphylococcus aureus bloodstream infection in South Korea: a prospective hospital-based nationwide study Kim, Chung-Jong Kim, Hong-Bin Oh, Myoung-don Kim, Yunhee Kim, Arim Oh, Sung-Hee Song, Kyoung-Ho Kim, Eu Suk Cho, Yong Kyun Choi, Young Hwa Park, Jinyong Kim, Baek-Nam Kim, Nam-Joong Kim, Kye-Hyung Lee, Eun Jung Jun, Jae-Bum Kim, Young Keun Kiem, Sung min Choi, Hee Jung Choo, Eun Ju Sohn, Kyung-mok Lee, Shinwon Chang, Hyun Ha Bang, Ji Hwan Lee, Su Jin Lee, Jae Hoon Park, Seong Yeon Jeon, Min Hyok Yun, Na Ra BMC Infect Dis Research Article BACKGROUND: We estimated the nationwide burden of nosocomial S. aureus bloodstream infection (SA-BSI), a major cause of nosocomial infection, in South Korea. METHODS: To evaluate the nationwide incidence of nosocomial SA-BSI, cases of SA-BSI were prospectively collected from 22 hospitals with over 500 beds over 4?months. Data on patient-days were obtained from a national health insurance database containing the claims data for all healthcare facilities in South Korea. The additional cost of SA-BSI was estimated through a matched case?control study. The economic burden was calculated from the sum of the medical costs, the costs of caregiving and loss of productivity. RESULTS: Three hundred and thirty nine cases of nosocomial SA-BSI were included in the study: 254 cases of methicillin-resistant SA-BSI (MRSA-BSI) and 85 cases of methicillin-susceptible SA-BSI (MSSA-BSI). Death related to BSI occurred in 81 cases (31.9%) of MRSA-BSI and 12 cases (14.1%) of MSSA-BSI. The estimated incidence of nosocomial MRSA-BSI was 0.12/1,000 patient-days and that of nosocomial MSSA-BSI, 0.04/1,000 patient-days. The estimated annual cases of nosocomial BSI were 2,946 for MRSA and 986 for MSSA in South Korea. The additional economic burden per case of nosocomial SA-BSI was US $20,494 for MRSA-BSI and $6,914 for MSSA-BSI. Total additional annual cost of nosocomial SA-BSI was $67,192,559. CONCLUSION: In view of the burden of nosocomial SA-BSI, a national strategy for reducing nosocomial SA-BSI is urgently needed in South Korea. ELECTRONIC SUPPLEMENTARY MATERIAL: The online version of this article (doi:10.1186/s12879-014-0590-4) contains supplementary material, which is available to authorized users. BioMed Central 2014-11-14 /pmc/articles/PMC4247623/ /pubmed/25891200 http://dx.doi.org/10.1186/s12879-014-0590-4 Text en © Kim et al.; licensee BioMed Central Ltd. 2014 This article is published under license to BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated. |
spellingShingle | Research Article Kim, Chung-Jong Kim, Hong-Bin Oh, Myoung-don Kim, Yunhee Kim, Arim Oh, Sung-Hee Song, Kyoung-Ho Kim, Eu Suk Cho, Yong Kyun Choi, Young Hwa Park, Jinyong Kim, Baek-Nam Kim, Nam-Joong Kim, Kye-Hyung Lee, Eun Jung Jun, Jae-Bum Kim, Young Keun Kiem, Sung min Choi, Hee Jung Choo, Eun Ju Sohn, Kyung-mok Lee, Shinwon Chang, Hyun Ha Bang, Ji Hwan Lee, Su Jin Lee, Jae Hoon Park, Seong Yeon Jeon, Min Hyok Yun, Na Ra The burden of nosocomial staphylococcus aureus bloodstream infection in South Korea: a prospective hospital-based nationwide study |
title | The burden of nosocomial staphylococcus aureus bloodstream infection in South Korea: a prospective hospital-based nationwide study |
title_full | The burden of nosocomial staphylococcus aureus bloodstream infection in South Korea: a prospective hospital-based nationwide study |
title_fullStr | The burden of nosocomial staphylococcus aureus bloodstream infection in South Korea: a prospective hospital-based nationwide study |
title_full_unstemmed | The burden of nosocomial staphylococcus aureus bloodstream infection in South Korea: a prospective hospital-based nationwide study |
title_short | The burden of nosocomial staphylococcus aureus bloodstream infection in South Korea: a prospective hospital-based nationwide study |
title_sort | burden of nosocomial staphylococcus aureus bloodstream infection in south korea: a prospective hospital-based nationwide study |
topic | Research Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4247623/ https://www.ncbi.nlm.nih.gov/pubmed/25891200 http://dx.doi.org/10.1186/s12879-014-0590-4 |
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