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Optogenetic activation of brainstem serotonergic neurons induces persistent pain sensitization

BACKGROUND: The rostral ventromedial medulla (RVM) is a key brainstem structure that conveys powerful descending influence of the central pain-modulating system on spinal pain transmission and processing. Serotonergic (5-HT) neurons are a major component in the heterogeneous populations of RVM neuro...

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Detalles Bibliográficos
Autores principales: Cai, You-Qing, Wang, Wei, Hou, Yuan-Yuan, Pan, Zhizhong Z
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4247651/
https://www.ncbi.nlm.nih.gov/pubmed/25410898
http://dx.doi.org/10.1186/1744-8069-10-70