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Pharmacogenomic analysis of retinoic-acid induced dyslipidemia in congenic rat model

BACKGROUND: All-trans retinoic acid (ATRA, tretinoin) is a vitamin A derivative commonly used in the treatment of diverse conditions ranging from cancer to acne. In a fraction of predisposed individuals, the administration of ATRA is accompanied by variety of adverse metabolic effects, particularly...

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Detalles Bibliográficos
Autores principales: Krupková, Michaela, Liška, František, Šedová, Lucie, Křenová, Drahomíra, Křen, Vladimír, Šeda, Ondřej
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4247747/
https://www.ncbi.nlm.nih.gov/pubmed/25403085
http://dx.doi.org/10.1186/1476-511X-13-172