Cargando…

How do research participants perceive “uncertainty” in genomic sequencing?

INTRODUCTION: The scope of uncertainty in genomic sequence information has no rival in health care delivery. We present data from adults participating in an NIH study using this technology where perceptions of uncertainty are hypothesized to be key in predicting decisions to learn and act on genomic...

Descripción completa

Detalles Bibliográficos
Autores principales:	Biesecker, Barbara B, Klein, William, Lewis, Katie L, Fisher, Tyler C, Wright, Martha Frances, Biesecker, Leslie G, Han, Paul K
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	2014
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4247806/ https://www.ncbi.nlm.nih.gov/pubmed/24875302 http://dx.doi.org/10.1038/gim.2014.57

Ejemplares similares

Preferences for results delivery from Exome Sequencing/Genome Sequencing: Genome results preferences
por: Wright, Martha Frances, et al.
Publicado: (2013)

Reactions to clinical reinterpretation of a gene variant by participants in a sequencing study
por: Taber, Jennifer M., et al.
Publicado: (2017)

Participant use and communication of findings from exome sequencing: A mixed methods study: Use and communication of findings from exome sequencing
por: Lewis, Katie L., et al.
Publicado: (2015)

Characterizing Participants in the ClinSeq Genome Sequencing Cohort as Early Adopters of a New Health Technology
por: Lewis, Katie L., et al.
Publicado: (2015)

A Taxonomy of Medical Uncertainties in Clinical Genome Sequencing
por: Han, Paul K. J., et al.
Publicado: (2017)

Health Behaviors Amongst Unaffected Participants Following Receipt of Variants of Uncertain Significance in Cardiomyopathy-Associated Genes
por: Miller, Ilana M., et al.
Publicado: (2018)

Dyadic concordance and associations of beliefs with intentions to learn carrier results from genomic sequencing
por: Huelsnitz, Chloe O., et al.
Publicado: (2021)

Ethnic identity and engagement with genome sequencing research
por: Turbitt, Erin, et al.
Publicado: (2018)

Characterization of Courtesy Stigma Perceived by Parents of Overweight Children with Bardet-Biedl Syndrome
por: Hamlington, Barbara, et al.
Publicado: (2015)

Hypothesis-generating clinical genomics research and predictive medicine
por: Biesecker, Leslie
Publicado: (2012)

Hypothesis-generating research and predictive medicine
por: Biesecker, Leslie G.
Publicado: (2013)

Cancer Patient Experience of Uncertainty While Waiting for Genome Sequencing Results
por: Bartley, Nicci, et al.
Publicado: (2021)

Genetic Testing and Other Healthcare Use by Black and White Individuals in a Genomic Sequencing Study
por: Saylor, Katherine W., et al.
Publicado: (2023)

Adaptation to bipolar disorder and perceived risk to children: a survey of parents with bipolar disorder
por: Peay, Holly L, et al.
Publicado: (2013)

Exome sequencing: the expert view
por: Biesecker, Leslie G, et al.
Publicado: (2011)

The Greig cephalopolysyndactyly syndrome
por: Biesecker, Leslie G
Publicado: (2008)

An introduction to standardized clinical nomenclature for dysmorphic features: the Elements of Morphology project
por: Biesecker, Leslie G
Publicado: (2010)

Genomic screening for monogenic forms of diabetes
por: Biesecker, Leslie G.
Publicado: (2018)

Mosaic Disorders and the Taxonomy of Human Disease
por: Biesecker, Leslie G.
Publicado: (2017)

Genomic screening and genomic diagnostic testing—two very different kettles of fish
por: Biesecker, Leslie G.
Publicado: (2019)

Mosaicism and the taxonomy of human disease
por: Biesecker, Leslie G.
Publicado: (2021)

Refining a Multifaceted Model of Perceived Utility of Genomic Sequencing Results
por: Duenas, Devan M., et al.
Publicado: (2023)

Determining the prevalence of McArdle disease from gene frequency by analysis of next generation sequencing data: McArdle prevalence by NGS data
por: De Castro, Mauricio, et al.
Publicado: (2015)

Parental coping with uncertainties along the severe combined immunodeficiency journey
por: Kutsa, Oksana, et al.
Publicado: (2022)

Approaches to informed consent for hypothesis-testing and hypothesis-generating clinical genomics research
por: Facio, Flavia M, et al.
Publicado: (2012)

Uncertainties experienced by parents of children diagnosed with severe combined immunodeficiency through newborn screening
por: Raspa, Melissa, et al.
Publicado: (2023)

Participation of medical students in patient care: How do patients perceive it?
por: Iqbal, Muhammad Zafar, et al.
Publicado: (2020)

Sports participation, perceived neighborhood safety, and individual cognitions: how do they interact?
por: Beenackers, Mariëlle A, et al.
Publicado: (2011)

Sports participation, perceived neighborhood safety, and individual cognitions: how do they interact?
por: Beenackers, Mariëlle A, et al.
Publicado: (2011)

SomatoSim: precision simulation of somatic single nucleotide variants
por: Hawari, Marwan A., et al.
Publicado: (2021)

A commentary on Actionable secondary findings in the 73 ACMG-recommended genes in 1,559 Thai exomes
por: Johnston, Jennifer J., et al.
Publicado: (2022)

Assessing the capability of massively parallel sequencing for opportunistic pharmacogenetic screening
por: Ng, David, et al.
Publicado: (2016)

Progression of skin lesions in Warburg-Cinotti syndrome
por: Ours, Christopher A., et al.
Publicado: (2021)

A systematic literature review of disclosure practices and reported outcomes for medically-actionable genomic secondary findings
por: Sapp, Julie C., et al.
Publicado: (2021)

Validation of the multidimensional impact of Cancer Risk Assessment Questionnaire to assess impact of waiting for genome sequencing results
por: Best, Megan, et al.
Publicado: (2022)

How Do Medical Students Perceive Their Research Experiences and Associated Challenges?
por: Alyousefi, Nada, et al.
Publicado: (2023)

How do users with comorbidity perceive participation in social services? A qualitative interview study
por: Jones, Amanda, et al.
Publicado: (2021)

How do we and how should we deal with uncertainty in endodontics?
por: Pigg, Maria, et al.
Publicado: (2022)

Assessing the reproducibility of exome copy number variations predictions
por: Hong, Celine S., et al.
Publicado: (2016)

A Perceived Zone of Certainty and Uncertainty: Propositions for Research Development
por: Phan, Huy P., et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_0iln641g2v33mgn759633cof9n