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Spinal Intramedullary Metastasis of Breast Cancer

Objective. Breast cancer accounts for approximately one-third of all cancers in females. Approximately 8.5 % of all central nervous system metastases are located in the spinal cord. These patients have rapidly progressing neurological deficits and require immediate examination. The aim of surgery is...

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Autores principales: Basaran, Recep, Tiryaki, Mehmet, Yavuzer, Dilek, Efendioglu, Mustafa, Balkuv, Ece, Sav, Aydin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4247914/
https://www.ncbi.nlm.nih.gov/pubmed/25477971
http://dx.doi.org/10.1155/2014/583282
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author Basaran, Recep
Tiryaki, Mehmet
Yavuzer, Dilek
Efendioglu, Mustafa
Balkuv, Ece
Sav, Aydin
author_facet Basaran, Recep
Tiryaki, Mehmet
Yavuzer, Dilek
Efendioglu, Mustafa
Balkuv, Ece
Sav, Aydin
author_sort Basaran, Recep
collection PubMed
description Objective. Breast cancer accounts for approximately one-third of all cancers in females. Approximately 8.5 % of all central nervous system metastases are located in the spinal cord. These patients have rapidly progressing neurological deficits and require immediate examination. The aim of surgery is decompression of neural tissue and histological evaluation of the tumor. In this paper, we present a case of breast cancer metastasis in thoracic spinal intramedullary area which had been partially excised and then given adjuvant radiotherapy. Case. A 43-year-old female patient with breast cancer for 8 years was admitted to our hospital with complaints of weakness in both legs. Eight years ago, she received chemotherapy and radiotherapy. On her neurological examination, she had paraparesis (left lower extremity: 2/5, right lower extremity: 3/5) and urinary incontinence. Spinal MRI revealed a gadolinium enhancing intramedullary lesion. Pathologic examination of the lesion was consistent with breast carcinoma metastasis. The patient has been taken into radiotherapy. Conclusion. Spinal intramedullary metastasis of breast cancer is an extremely rare situation, but it has a high morbidity and mortality rate. Microsurgical resection is necessary for preservation or amelioration of neurological state and also for increased life expectancy and quality.
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spelling pubmed-42479142014-12-04 Spinal Intramedullary Metastasis of Breast Cancer Basaran, Recep Tiryaki, Mehmet Yavuzer, Dilek Efendioglu, Mustafa Balkuv, Ece Sav, Aydin Case Rep Med Case Report Objective. Breast cancer accounts for approximately one-third of all cancers in females. Approximately 8.5 % of all central nervous system metastases are located in the spinal cord. These patients have rapidly progressing neurological deficits and require immediate examination. The aim of surgery is decompression of neural tissue and histological evaluation of the tumor. In this paper, we present a case of breast cancer metastasis in thoracic spinal intramedullary area which had been partially excised and then given adjuvant radiotherapy. Case. A 43-year-old female patient with breast cancer for 8 years was admitted to our hospital with complaints of weakness in both legs. Eight years ago, she received chemotherapy and radiotherapy. On her neurological examination, she had paraparesis (left lower extremity: 2/5, right lower extremity: 3/5) and urinary incontinence. Spinal MRI revealed a gadolinium enhancing intramedullary lesion. Pathologic examination of the lesion was consistent with breast carcinoma metastasis. The patient has been taken into radiotherapy. Conclusion. Spinal intramedullary metastasis of breast cancer is an extremely rare situation, but it has a high morbidity and mortality rate. Microsurgical resection is necessary for preservation or amelioration of neurological state and also for increased life expectancy and quality. Hindawi Publishing Corporation 2014 2014-11-13 /pmc/articles/PMC4247914/ /pubmed/25477971 http://dx.doi.org/10.1155/2014/583282 Text en Copyright © 2014 Recep Basaran et al. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Basaran, Recep
Tiryaki, Mehmet
Yavuzer, Dilek
Efendioglu, Mustafa
Balkuv, Ece
Sav, Aydin
Spinal Intramedullary Metastasis of Breast Cancer
title Spinal Intramedullary Metastasis of Breast Cancer
title_full Spinal Intramedullary Metastasis of Breast Cancer
title_fullStr Spinal Intramedullary Metastasis of Breast Cancer
title_full_unstemmed Spinal Intramedullary Metastasis of Breast Cancer
title_short Spinal Intramedullary Metastasis of Breast Cancer
title_sort spinal intramedullary metastasis of breast cancer
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4247914/
https://www.ncbi.nlm.nih.gov/pubmed/25477971
http://dx.doi.org/10.1155/2014/583282
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