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Male Pelvic Squamous Cell Carcinoma of Unknown Primary Origin

Pelvic squamous cell carcinoma of unknown primary origin has been described in several case reports of female patients. However, there have been no published reports describing male patients with pelvic squamous cell cancer of unknown primary origin. Our case describes a 52-year-old man who presente...

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Autores principales: Chiec, Lauren, Verma, Sadhna, Kendler, Ady, Abdel Karim, Nagla
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4247932/
https://www.ncbi.nlm.nih.gov/pubmed/25478265
http://dx.doi.org/10.1155/2014/953698
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author Chiec, Lauren
Verma, Sadhna
Kendler, Ady
Abdel Karim, Nagla
author_facet Chiec, Lauren
Verma, Sadhna
Kendler, Ady
Abdel Karim, Nagla
author_sort Chiec, Lauren
collection PubMed
description Pelvic squamous cell carcinoma of unknown primary origin has been described in several case reports of female patients. However, there have been no published reports describing male patients with pelvic squamous cell cancer of unknown primary origin. Our case describes a 52-year-old man who presented with right buttock pain, rectal urgency, and constipation. His physical examination demonstrated tenderness to palpation around his gluteal folds. Computed tomography scan of his abdomen and pelvis demonstrated a large mass in his retroperitoneum. The mass was determined to be squamous cell carcinoma of unknown primary origin. Additionally, the patient had small nodules in his right lower lung lobe and right hepatic lobe. The patient was treated with concomitant chemoradiation, including cisplatin and intensity-modulated radiation therapy, followed by carboplatin and paclitaxel. The patient achieved partial remission, in which he remained one year after his presentation. Our case is consistent with the literature which suggests that squamous cell carcinoma of unknown primary origin occurring outside of the head and neck region may have a more favorable prognosis than other carcinomas of unknown primary origin. Further studies are necessary to determine the most appropriate work-up, diagnosis, and optimal treatment strategies.
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spelling pubmed-42479322014-12-04 Male Pelvic Squamous Cell Carcinoma of Unknown Primary Origin Chiec, Lauren Verma, Sadhna Kendler, Ady Abdel Karim, Nagla Case Rep Oncol Med Case Report Pelvic squamous cell carcinoma of unknown primary origin has been described in several case reports of female patients. However, there have been no published reports describing male patients with pelvic squamous cell cancer of unknown primary origin. Our case describes a 52-year-old man who presented with right buttock pain, rectal urgency, and constipation. His physical examination demonstrated tenderness to palpation around his gluteal folds. Computed tomography scan of his abdomen and pelvis demonstrated a large mass in his retroperitoneum. The mass was determined to be squamous cell carcinoma of unknown primary origin. Additionally, the patient had small nodules in his right lower lung lobe and right hepatic lobe. The patient was treated with concomitant chemoradiation, including cisplatin and intensity-modulated radiation therapy, followed by carboplatin and paclitaxel. The patient achieved partial remission, in which he remained one year after his presentation. Our case is consistent with the literature which suggests that squamous cell carcinoma of unknown primary origin occurring outside of the head and neck region may have a more favorable prognosis than other carcinomas of unknown primary origin. Further studies are necessary to determine the most appropriate work-up, diagnosis, and optimal treatment strategies. Hindawi Publishing Corporation 2014 2014-11-13 /pmc/articles/PMC4247932/ /pubmed/25478265 http://dx.doi.org/10.1155/2014/953698 Text en Copyright © 2014 Lauren Chiec et al. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Chiec, Lauren
Verma, Sadhna
Kendler, Ady
Abdel Karim, Nagla
Male Pelvic Squamous Cell Carcinoma of Unknown Primary Origin
title Male Pelvic Squamous Cell Carcinoma of Unknown Primary Origin
title_full Male Pelvic Squamous Cell Carcinoma of Unknown Primary Origin
title_fullStr Male Pelvic Squamous Cell Carcinoma of Unknown Primary Origin
title_full_unstemmed Male Pelvic Squamous Cell Carcinoma of Unknown Primary Origin
title_short Male Pelvic Squamous Cell Carcinoma of Unknown Primary Origin
title_sort male pelvic squamous cell carcinoma of unknown primary origin
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4247932/
https://www.ncbi.nlm.nih.gov/pubmed/25478265
http://dx.doi.org/10.1155/2014/953698
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