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Outcomes of Renal Transplantation in Brunei Darussalam over a Twenty-Year Period (1993–2012)

Objectives. Brunei Darussalam has a high prevalence and incidence of end stage renal disease (ESRD). Up until 2012, all renal transplantations were performed in overseas centres, either as government-sponsored (living-related transplantation) or as self-sponsored (commercialized transplantation) one...

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Autores principales: Tan, Jackson, Khalil, Muhammad Abdul Mabood, Tan, Si Yen, Khalil, Muhammad, Ahmed, Dalinatul, Zinna, Shaukat, Chong, William
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4247949/
https://www.ncbi.nlm.nih.gov/pubmed/25478205
http://dx.doi.org/10.1155/2014/784805
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author Tan, Jackson
Khalil, Muhammad Abdul Mabood
Tan, Si Yen
Khalil, Muhammad
Ahmed, Dalinatul
Zinna, Shaukat
Chong, William
author_facet Tan, Jackson
Khalil, Muhammad Abdul Mabood
Tan, Si Yen
Khalil, Muhammad
Ahmed, Dalinatul
Zinna, Shaukat
Chong, William
author_sort Tan, Jackson
collection PubMed
description Objectives. Brunei Darussalam has a high prevalence and incidence of end stage renal disease (ESRD). Up until 2012, all renal transplantations were performed in overseas centres, either as government-sponsored (living-related transplantation) or as self-sponsored (commercialized transplantation) ones. We hypothesize that graft and patient survival of Brunei renal transplant patients are on a par with international standards. Materials and Methods. Data of all renal transplant patients in Brunei were analysed over a twenty-year period from registry records and case notes. Comparative survival data from other countries were obtained from PubMed-listed literature. Results. A total of 49 transplantation procedures were performed in foreign centres between 1993 and 2012. 29 were government-sponsored and 20 were self-sponsored transplantations. The 5- and 10-year overall patient survival rates were 93.3% and 90.1%, respectively. The 5- and 10-year overall graft survival rates were 91.1% and 81.2%. There is no difference in the survival outcomes of government-sponsored and self-sponsored patients. Living-related (government-sponsored) and commercialised (self-sponsored) grafts had equivalent survival to those reported in the literature. Conclusion. Our survival data was on par with those achieved in many countries. We hope to use this information to convince local stakeholders and patients to favour transplantation as the preferred modality of RRT.
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spelling pubmed-42479492014-12-04 Outcomes of Renal Transplantation in Brunei Darussalam over a Twenty-Year Period (1993–2012) Tan, Jackson Khalil, Muhammad Abdul Mabood Tan, Si Yen Khalil, Muhammad Ahmed, Dalinatul Zinna, Shaukat Chong, William J Transplant Research Article Objectives. Brunei Darussalam has a high prevalence and incidence of end stage renal disease (ESRD). Up until 2012, all renal transplantations were performed in overseas centres, either as government-sponsored (living-related transplantation) or as self-sponsored (commercialized transplantation) ones. We hypothesize that graft and patient survival of Brunei renal transplant patients are on a par with international standards. Materials and Methods. Data of all renal transplant patients in Brunei were analysed over a twenty-year period from registry records and case notes. Comparative survival data from other countries were obtained from PubMed-listed literature. Results. A total of 49 transplantation procedures were performed in foreign centres between 1993 and 2012. 29 were government-sponsored and 20 were self-sponsored transplantations. The 5- and 10-year overall patient survival rates were 93.3% and 90.1%, respectively. The 5- and 10-year overall graft survival rates were 91.1% and 81.2%. There is no difference in the survival outcomes of government-sponsored and self-sponsored patients. Living-related (government-sponsored) and commercialised (self-sponsored) grafts had equivalent survival to those reported in the literature. Conclusion. Our survival data was on par with those achieved in many countries. We hope to use this information to convince local stakeholders and patients to favour transplantation as the preferred modality of RRT. Hindawi Publishing Corporation 2014 2014-11-12 /pmc/articles/PMC4247949/ /pubmed/25478205 http://dx.doi.org/10.1155/2014/784805 Text en Copyright © 2014 Jackson Tan et al. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Research Article
Tan, Jackson
Khalil, Muhammad Abdul Mabood
Tan, Si Yen
Khalil, Muhammad
Ahmed, Dalinatul
Zinna, Shaukat
Chong, William
Outcomes of Renal Transplantation in Brunei Darussalam over a Twenty-Year Period (1993–2012)
title Outcomes of Renal Transplantation in Brunei Darussalam over a Twenty-Year Period (1993–2012)
title_full Outcomes of Renal Transplantation in Brunei Darussalam over a Twenty-Year Period (1993–2012)
title_fullStr Outcomes of Renal Transplantation in Brunei Darussalam over a Twenty-Year Period (1993–2012)
title_full_unstemmed Outcomes of Renal Transplantation in Brunei Darussalam over a Twenty-Year Period (1993–2012)
title_short Outcomes of Renal Transplantation in Brunei Darussalam over a Twenty-Year Period (1993–2012)
title_sort outcomes of renal transplantation in brunei darussalam over a twenty-year period (1993–2012)
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4247949/
https://www.ncbi.nlm.nih.gov/pubmed/25478205
http://dx.doi.org/10.1155/2014/784805
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