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The evolution of thymic lymphomas in p53 knockout mice

Germline deletion of the p53 gene in mice gives rise to spontaneous thymic (T-cell) lymphomas. In this study, the p53 knockout mouse was employed as a model to study the mutational evolution of tumorigenesis. The clonality of the T-cell repertoire from p53 knockout and wild-type thymic cells was ana...

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Detalles Bibliográficos
Autores principales:	Dudgeon, Crissy, Chan, Chang, Kang, Wenfeng, Sun, Yvonne, Emerson, Ryan, Robins, Harlan, Levine, Arnold J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Cold Spring Harbor Laboratory Press 2014
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4248292/ https://www.ncbi.nlm.nih.gov/pubmed/25452272 http://dx.doi.org/10.1101/gad.252148.114

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