Prevalence of pfmdr1 alleles associated with artemether-lumefantrine tolerance/resistance in Maputo before and after the implementation of artemisinin-based combination therapy

BACKGROUND: Mozambique implemented artemisinin-based combinations therapy (ACT) using artemether-lumefantrine (AL) as the first-line treatment for uncomplicated malaria in 2009. AL remains highly efficacious, but widespread use may soon facilitate emergence of artemisinin tolerance/resistance. The p...

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Detalles Bibliográficos
Autores principales: Lobo, Elsa, de Sousa, Bruno, Rosa, Soraia, Figueiredo, Paula, Lobo, Lis, Pateira, Sara, Fernandes, Natercia, Nogueira, Fatima
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4248432/
https://www.ncbi.nlm.nih.gov/pubmed/25098280
http://dx.doi.org/10.1186/1475-2875-13-300

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4248432/
https://www.ncbi.nlm.nih.gov/pubmed/25098280
http://dx.doi.org/10.1186/1475-2875-13-300

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