Bullous Lesions, Sweat Gland Necrosis and Rhabdomyolysis in Alcoholic Coma

A 42-year-old male developed hemorrhagic bullae and erosions while in alcohol induced coma. The lesions were limited to areas of the body in prolonged contact with the ground in the comatose state. He developed rhabdomyolysis, progressing to acute renal failure (ARF). Histopathological examination o...

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Autores principales: Asokan, Neelakandhan, Binesh, Vayappurath Gangadharan, Andrews, Andrews Mekkattukunnel, Jayalakshmi, Pattomthadathil Sankaran
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2014
Materias:
E-IJD Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4248528/
https://www.ncbi.nlm.nih.gov/pubmed/25484420
http://dx.doi.org/10.4103/0019-5154.143576
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author Asokan, Neelakandhan
Binesh, Vayappurath Gangadharan
Andrews, Andrews Mekkattukunnel
Jayalakshmi, Pattomthadathil Sankaran
author_facet Asokan, Neelakandhan
Binesh, Vayappurath Gangadharan
Andrews, Andrews Mekkattukunnel
Jayalakshmi, Pattomthadathil Sankaran
author_sort Asokan, Neelakandhan
collection PubMed
description A 42-year-old male developed hemorrhagic bullae and erosions while in alcohol induced coma. The lesions were limited to areas of the body in prolonged contact with the ground in the comatose state. He developed rhabdomyolysis, progressing to acute renal failure (ARF). Histopathological examination of the skin showed spongiosis, intraepidermal vesicles, and necrosis of eccrine sweat glands with denudation of secretory epithelial lining cells. With supportive treatment and hemodialysis, the patient recovered in 3 weeks time. This is the first reported case of bullous lesions and sweat gland necrosis occurring in alcohol-induced coma complicated by rhabdomyolysis and ARF.
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spelling pubmed-42485282014-12-05 Bullous Lesions, Sweat Gland Necrosis and Rhabdomyolysis in Alcoholic Coma Asokan, Neelakandhan Binesh, Vayappurath Gangadharan Andrews, Andrews Mekkattukunnel Jayalakshmi, Pattomthadathil Sankaran Indian J Dermatol E-IJD Case Report A 42-year-old male developed hemorrhagic bullae and erosions while in alcohol induced coma. The lesions were limited to areas of the body in prolonged contact with the ground in the comatose state. He developed rhabdomyolysis, progressing to acute renal failure (ARF). Histopathological examination of the skin showed spongiosis, intraepidermal vesicles, and necrosis of eccrine sweat glands with denudation of secretory epithelial lining cells. With supportive treatment and hemodialysis, the patient recovered in 3 weeks time. This is the first reported case of bullous lesions and sweat gland necrosis occurring in alcohol-induced coma complicated by rhabdomyolysis and ARF. Medknow Publications & Media Pvt Ltd 2014 /pmc/articles/PMC4248528/ /pubmed/25484420 http://dx.doi.org/10.4103/0019-5154.143576 Text en Copyright: © Indian Journal of Dermatology http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open-access article distributed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle E-IJD Case Report
Asokan, Neelakandhan
Binesh, Vayappurath Gangadharan
Andrews, Andrews Mekkattukunnel
Jayalakshmi, Pattomthadathil Sankaran
Bullous Lesions, Sweat Gland Necrosis and Rhabdomyolysis in Alcoholic Coma
title Bullous Lesions, Sweat Gland Necrosis and Rhabdomyolysis in Alcoholic Coma
title_full Bullous Lesions, Sweat Gland Necrosis and Rhabdomyolysis in Alcoholic Coma
title_fullStr Bullous Lesions, Sweat Gland Necrosis and Rhabdomyolysis in Alcoholic Coma
title_full_unstemmed Bullous Lesions, Sweat Gland Necrosis and Rhabdomyolysis in Alcoholic Coma
title_short Bullous Lesions, Sweat Gland Necrosis and Rhabdomyolysis in Alcoholic Coma
title_sort bullous lesions, sweat gland necrosis and rhabdomyolysis in alcoholic coma
topic E-IJD Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4248528/
https://www.ncbi.nlm.nih.gov/pubmed/25484420
http://dx.doi.org/10.4103/0019-5154.143576
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