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Mid-Term Outcomes in Patients Implanted with Cardiac Resynchronization Therapy

We applied cardiac resynchronization therapy (CRT) for desynchronized heart failure patients. We evaluated clinical outcomes including morbidity, mortality, and echocardiographic parameters in 47 patients with implanted CRT in Korea from October 2005 to May 2013. The combined outcomes of hospitaliza...

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Autores principales: Lee, Sung Ho, Park, Seung-Jung, Kim, June Soo, Shin, Dae-Hee, Cho, Dae Kyoung, On, Young Keun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Academy of Medical Sciences 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4248586/
https://www.ncbi.nlm.nih.gov/pubmed/25469065
http://dx.doi.org/10.3346/jkms.2014.29.12.1651
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author Lee, Sung Ho
Park, Seung-Jung
Kim, June Soo
Shin, Dae-Hee
Cho, Dae Kyoung
On, Young Keun
author_facet Lee, Sung Ho
Park, Seung-Jung
Kim, June Soo
Shin, Dae-Hee
Cho, Dae Kyoung
On, Young Keun
author_sort Lee, Sung Ho
collection PubMed
description We applied cardiac resynchronization therapy (CRT) for desynchronized heart failure patients. We evaluated clinical outcomes including morbidity, mortality, and echocardiographic parameters in 47 patients with implanted CRT in Korea from October 2005 to May 2013. The combined outcomes of hospitalization from heart failure, heart transplantation and death were the primary end point. Median follow-up period was 17.5 months. The primary outcomes listed above occurred in 10 (21.3%) patients. Two patients (4.3%) died after CRT and 8 (17%) patients were hospitalized for recurrent heart failure. Among patients hospitalized for heart failure, 2 (4.3%) patients underwent heart transplantation. The overall free rate of heart failure requiring hospitalization was 90.1% (95% CI, 0.81-0.99) over one year and 69.4% (95% CI, 0.47-0.91) over 3 yr. We observed improvement of the New York Heart Association classification (3.1±0.5 to 1.7±0.4), decreases in QRS duration (169.1 to 146.9 ms), decreases in left ventricular (LV) end-diastolic (255.0 to 220.1 mL) and end-systolic (194.4 to 159.4 mL) volume and increases in LV ejection fraction (22.5% to 31.1%) at 6 months after CRT. CRT improved symptoms and echocardiographic parameters in a relatively short period, resulting in low mortality and a decrease in hospitalization due to heart failure.
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spelling pubmed-42485862014-12-02 Mid-Term Outcomes in Patients Implanted with Cardiac Resynchronization Therapy Lee, Sung Ho Park, Seung-Jung Kim, June Soo Shin, Dae-Hee Cho, Dae Kyoung On, Young Keun J Korean Med Sci Original Article We applied cardiac resynchronization therapy (CRT) for desynchronized heart failure patients. We evaluated clinical outcomes including morbidity, mortality, and echocardiographic parameters in 47 patients with implanted CRT in Korea from October 2005 to May 2013. The combined outcomes of hospitalization from heart failure, heart transplantation and death were the primary end point. Median follow-up period was 17.5 months. The primary outcomes listed above occurred in 10 (21.3%) patients. Two patients (4.3%) died after CRT and 8 (17%) patients were hospitalized for recurrent heart failure. Among patients hospitalized for heart failure, 2 (4.3%) patients underwent heart transplantation. The overall free rate of heart failure requiring hospitalization was 90.1% (95% CI, 0.81-0.99) over one year and 69.4% (95% CI, 0.47-0.91) over 3 yr. We observed improvement of the New York Heart Association classification (3.1±0.5 to 1.7±0.4), decreases in QRS duration (169.1 to 146.9 ms), decreases in left ventricular (LV) end-diastolic (255.0 to 220.1 mL) and end-systolic (194.4 to 159.4 mL) volume and increases in LV ejection fraction (22.5% to 31.1%) at 6 months after CRT. CRT improved symptoms and echocardiographic parameters in a relatively short period, resulting in low mortality and a decrease in hospitalization due to heart failure. The Korean Academy of Medical Sciences 2014-12 2014-11-21 /pmc/articles/PMC4248586/ /pubmed/25469065 http://dx.doi.org/10.3346/jkms.2014.29.12.1651 Text en © 2014 The Korean Academy of Medical Sciences. http://creativecommons.org/licenses/by-nc/4.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Original Article
Lee, Sung Ho
Park, Seung-Jung
Kim, June Soo
Shin, Dae-Hee
Cho, Dae Kyoung
On, Young Keun
Mid-Term Outcomes in Patients Implanted with Cardiac Resynchronization Therapy
title Mid-Term Outcomes in Patients Implanted with Cardiac Resynchronization Therapy
title_full Mid-Term Outcomes in Patients Implanted with Cardiac Resynchronization Therapy
title_fullStr Mid-Term Outcomes in Patients Implanted with Cardiac Resynchronization Therapy
title_full_unstemmed Mid-Term Outcomes in Patients Implanted with Cardiac Resynchronization Therapy
title_short Mid-Term Outcomes in Patients Implanted with Cardiac Resynchronization Therapy
title_sort mid-term outcomes in patients implanted with cardiac resynchronization therapy
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4248586/
https://www.ncbi.nlm.nih.gov/pubmed/25469065
http://dx.doi.org/10.3346/jkms.2014.29.12.1651
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