Cargando…

Latency-Associated Viral Interleukin-10 (IL-10) Encoded by Human Cytomegalovirus Modulates Cellular IL-10 and CCL8 Secretion during Latent Infection through Changes in the Cellular MicroRNA hsa-miR-92a

The UL111A gene of human cytomegalovirus encodes a viral homologue of the cellular immunomodulatory cytokine interleukin 10 (cIL-10), which, due to alternative splicing, results in expression of two isoforms designated LAcmvIL-10 (expressed during both lytic and latent infection) and cmvIL-10 (ident...

Descripción completa

Detalles Bibliográficos
Autores principales:	Poole, Emma, Avdic, Selmir, Hodkinson, Jemima, Jackson, Sarah, Wills, Mark, Slobedman, Barry, Sinclair, John
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Microbiology 2014
Materias:	Cellular Response to Infection
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4249158/ https://www.ncbi.nlm.nih.gov/pubmed/25253336 http://dx.doi.org/10.1128/JVI.02424-14

Ejemplares similares

Modulation of dendritic cell functions by viral IL-10 encoded by human cytomegalovirus
por: Avdic, Selmir, et al.
Publicado: (2014)

Human Cytomegalovirus Latency-Associated Proteins Elicit Immune-Suppressive IL-10 Producing CD4(+) T Cells
por: Mason, Gavin M., et al.
Publicado: (2013)

Human Cytomegalovirus Latency and Reactivation in Allogeneic Hematopoietic Stem Cell Transplant Recipients
por: Stern, Lauren, et al.
Publicado: (2019)

Latent infection of myeloid progenitors by human cytomegalovirus protects cells from FAS-mediated apoptosis through the cellular IL-10/PEA-15 pathway
por: Poole, Emma, et al.
Publicado: (2015)

Human Cytomegalovirus Encoded Homologs of Cytokines, Chemokines and their Receptors: Roles in Immunomodulation
por: McSharry, Brian P., et al.
Publicado: (2012)

Evaluation of the Effect of Cellular Phones on Salivary Levels of IL-10
por: PEDRAMI, Ali, et al.
Publicado: (2019)

Viral interleukin 10 (IL-10), the human herpes virus 4 cellular IL-10 homologue, induces local anergy to allogeneic and syngeneic tumors
Publicado: (1995)

IL-10-Secreting CD8(+) T Cells Specific for Human Cytomegalovirus (HCMV): Generation, Maintenance and Phenotype
por: Jackson, Sarah E., et al.
Publicado: (2022)

Sleepless latency of human cytomegalovirus
por: Poole, Emma, et al.
Publicado: (2015)

T Cell–Derived IL-10 Impairs Host Resistance to Mycobacterium tuberculosis Infection
por: Moreira-Teixeira, Lúcia, et al.
Publicado: (2017)

Yersiniabactin-Producing Adherent/Invasive Escherichia coli Promotes Inflammation-Associated Fibrosis in Gnotobiotic Il10(−/−) Mice
por: Ellermann, Melissa, et al.
Publicado: (2019)

Cytomegalovirus exploits IL-10–mediated immune regulation in the salivary glands
por: Humphreys, Ian R., et al.
Publicado: (2007)

Association of IL10, IL10RA, and IL10RB Polymorphisms with Benign Prostate Hyperplasia in Korean Population
por: Yoo, Koo Han, et al.
Publicado: (2011)

IL-10-dependent partial refractoriness to Toll-like receptor stimulation modulates gut mucosal dendritic cell function
por: Monteleone, Ivan, et al.
Publicado: (2008)

IL-4, IL-10, CCL2 and TGF-β as potential biomarkers for severity in Plasmodium vivax malaria
por: Tovar Acero, Catalina, et al.
Publicado: (2022)

Circulating cytokine and chemokine patterns associated with cytomegalovirus reactivation after stem cell transplantation
por: Stern, Lauren, et al.
Publicado: (2023)

Type I IFN Induces IL-10 Production in an IL-27–Independent Manner and Blocks Responsiveness to IFN-γ for Production of IL-12 and Bacterial Killing in Mycobacterium tuberculosis–Infected Macrophages
por: McNab, Finlay W., et al.
Publicado: (2014)

Molecular modelling of the HCMV IL-10 protein isoforms and analysis of their interaction with the human IL-10 receptor
por: Pantaleão, Simone Queiroz, et al.
Publicado: (2022)

LIN92#10
Publicado: (1992)

EXM 92-10
por: Daems, G
Publicado: (1992)

Correction: Molecular modelling of the HCMV IL-10 protein isoforms and analysis of their interaction with the human IL-10 receptor
por: Pantaleão, Simone Queiroz, et al.
Publicado: (2023)

Single cell analysis reveals human cytomegalovirus drives latently infected cells towards an anergic-like monocyte state
por: Shnayder, Miri, et al.
Publicado: (2020)

Circulating IL-6, IL-10, and TNF-alpha and IL-10/IL-6 and IL-10/TNF-alpha ratio profiles of polyparasitized individuals in rural and urban areas of gabon
por: M’Bondoukwé, Noé Patrick, et al.
Publicado: (2022)

Human Cytomegalovirus Interleukin 10 Homologs: Facing the Immune System
por: Poole, Emma, et al.
Publicado: (2020)

EXM 92-21 29/10/92
por: Daems, G
Publicado: (1992)

IL10 inhibits starvation-induced autophagy in hypertrophic scar fibroblasts via cross talk between the IL10-IL10R-STAT3 and IL10-AKT-mTOR pathways
por: Shi, J, et al.
Publicado: (2016)

NK Cell IL-10 Production Requires IL-15 and IL-10 Driven STAT3 Activation
por: Clark, Sarah E., et al.
Publicado: (2019)

Interleukin 10(IL-10) inhibits cytokine synthesis by human monocytes: an autoregulatory role of IL-10 produced by monocytes
Publicado: (1991)

Dogs immunized with LBSap vaccine displayed high levels of IL-12 and IL-10 cytokines and CCL4, CCL5 and CXCL8 chemokines in the dermis
por: Vitoriano-Souza, Juliana, et al.
Publicado: (2013)

IL-10 Mediated Regulation of Liver Inflammation during Acute Murine Cytomegalovirus Infection
por: Gaddi, Pamela J., et al.
Publicado: (2012)

92 Serum CTLA-4 AND IL-10 in Hymenoptera Venom Immunotherapy: Equivalence of Different Induction Regimens
por: Riccio, Anna Maria, et al.
Publicado: (2012)

Design and Analysis of Rhesus Cytomegalovirus IL-10 Mutants as a Model for Novel Vaccines against Human Cytomegalovirus
por: Logsdon, Naomi J., et al.
Publicado: (2011)

Four-Parameter FluoroSpot Assay Reveals That the Varicella Zoster Virus Elicits a Robust Memory T Cell IL-10 Response throughout Childhood
por: Nilsson, Anna, et al.
Publicado: (2022)

Polyinosinic: Polycytidylic Acid and Murine Cytomegalovirus Modulate Expression of Murine IL-10 and IL-21 in White Adipose Tissue
por: Garcia-Valtanen, Pablo, et al.
Publicado: (2020)

Immunoprofiling reveals cell subsets associated with the trajectory of cytomegalovirus reactivation post stem cell transplantation
por: Stern, Lauren, et al.
Publicado: (2022)

Zebrafish IL-4–like Cytokines and IL-10 Suppress Inflammation but Only IL-10 Is Essential for Gill Homeostasis
por: Bottiglione, Federica, et al.
Publicado: (2020)

IL-10 and IL-10 Receptor Mutations in Very Early Onset Inflammatory Bowel Disease
por: Zhu, Lei, et al.
Publicado: (2017)

Association of Interleukin Genes IL10 and IL10RB with Parameters of Overweight in Military Students
por: Maculewicz, Ewelina, et al.
Publicado: (2022)

IL-10 Gene Polymorphisms and IL-10 Serum Levels in Patients with Multiple Sclerosis in Lithuania
por: Masilionyte, Ugne, et al.
Publicado: (2022)

The regulatory role of differential microRNA expressions on cellular inflammatory factors IL‐6 and IL‐10 in Echinococcus granulosus‐induced anaphylaxis
por: Wang, Chun‐sheng, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_7ffrbii7ci1d803bvpu5qe9j30