Profilin-1 suppresses tumorigenicity in pancreatic cancer through regulation of the SIRT3-HIF1α axis

BACKGROUND: Tumor cells exhibit abnormal actin remodeling profiles, which involve the altered expressions of several important actin-binding proteins. Profilin1 (Pfn1), originally identified as an actin-associated protein, has been linked to several human malignancies. Our recent studies suggested t...

Descripción completa

Detalles Bibliográficos
Autores principales: Yao, Wantong, Ji, Shunrong, Qin, Yi, Yang, Jingxuan, Xu, Jin, Zhang, Bo, Xu, Wenyan, Liu, Jiang, Shi, Si, Liu, Liang, Liu, Chen, Long, Jiang, Ni, Quanxing, Li, Min, Yu, Xianjun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4249601/
https://www.ncbi.nlm.nih.gov/pubmed/25103363
http://dx.doi.org/10.1186/1476-4598-13-187

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4249601/
https://www.ncbi.nlm.nih.gov/pubmed/25103363
http://dx.doi.org/10.1186/1476-4598-13-187

Ejemplares similares