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Mapping and manipulating the Mycobacterium tuberculosis transcriptome using a transcription factor overexpression-derived regulatory network

BACKGROUND: Mycobacterium tuberculosis senses and responds to the shifting and hostile landscape of the host. To characterize the underlying intertwined gene regulatory network governed by approximately 200 transcription factors of M. tuberculosis, we have assayed the global transcriptional conseque...

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Detalles Bibliográficos
Autores principales: Rustad, Tige R, Minch, Kyle J, Ma, Shuyi, Winkler, Jessica K, Hobbs, Samuel, Hickey, Mark, Brabant, William, Turkarslan, Serdar, Price, Nathan D, Baliga, Nitin S, Sherman, David R
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4249609/
https://www.ncbi.nlm.nih.gov/pubmed/25380655
http://dx.doi.org/10.1186/s13059-014-0502-3