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A HIF-1 network reveals characteristics of epithelial-mesenchymal transition in acute promyelocytic leukemia

BACKGROUND: Acute promyelocytic leukemia (APL) is a sub-type of acute myeloid leukemia (AML) characterized by a block of myeloid differentiation at the promyelocytic stage and the predominant t(15:17) chromosomal translocation. We have previously determined that cells from APL patients show increase...

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Detalles Bibliográficos
Autores principales: Percio, Stefano, Coltella, Nadia, Grisanti, Sara, Bernardi, Rosa, Pattini, Linda
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4249615/
https://www.ncbi.nlm.nih.gov/pubmed/25452766
http://dx.doi.org/10.1186/s13073-014-0084-4