Cargando…

Exogenous c-Myc Blocks Differentiation and Improves Expansion of Human Erythroblasts In vitro

BACKGROUND: Engineered blood has the greatest potential to combat a predicted future shortfall in the blood supply for transfusion treatment. The production of red blood cells from hematopoietic stem cells in the laboratory is possible but the mass production of red blood cells to the level present...

Descripción completa

Detalles Bibliográficos
Autores principales:	Geiler, Cristopher, Andrade, Inez, Greenwald, Daniel
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Korean Society for Stem Cell Research 2014
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4249898/ https://www.ncbi.nlm.nih.gov/pubmed/25473453 http://dx.doi.org/10.15283/ijsc.2014.7.2.153

Ejemplares similares

Genetically Engineered In Vitro Erythropoiesis
por: Geiler, Cristopher, et al.
Publicado: (2016)

Expansion and differentiation of ex vivo cultured erythroblasts in scalable stirred bioreactors
por: Gallego‐Murillo, Joan Sebastián, et al.
Publicado: (2022)

Garland of Erythroblasts around a Macrophage: Erythroblastic Island
por: Kumar, Chandan, et al.
Publicado: (2020)

Protein Distribution during Human Erythroblast Enucleation In Vitro
por: Bell, Amanda J., et al.
Publicado: (2013)

Scalable in vitro production of defined mouse erythroblasts
por: Francis, Helena S., et al.
Publicado: (2022)

Erythroblast Enucleation
por: Keerthivasan, Ganesan, et al.
Publicado: (2011)

Immortalization of Erythroblasts by c-MYC and BCL-XL Enables Large-Scale Erythrocyte Production from Human Pluripotent Stem Cells
por: Hirose, Sho-ichi, et al.
Publicado: (2013)

RHEX, a novel regulator of human erythroid progenitor cell expansion and erythroblast development
por: Verma, Rakesh, et al.
Publicado: (2014)

RHEX, a novel regulator of human erythroid progenitor cell expansion and erythroblast development
por: Verma, Rakesh, et al.
Publicado: (2015)

Cooley's Erythroblastic Anæmia
por: Parekh, J. G.
Publicado: (1940)

Cooley's Erythroblastic Anæmia
por: Napier, L. Everard, et al.
Publicado: (1939)

BMI1 enables extensive expansion of functional erythroblasts from human peripheral blood mononuclear cells
por: Liu, Senquan, et al.
Publicado: (2021)

Overexpression of miR-669m inhibits erythroblast differentiation
por: Kotaki, Ryutaro, et al.
Publicado: (2020)

Expansion of EPOR-negative macrophages besides erythroblasts by elevated EPOR signaling in erythrocytosis mouse models
por: Wang, Jieyu, et al.
Publicado: (2018)

THE MECHANISM OF DENUCLEATION IN CIRCULATING ERYTHROBLASTS
por: Simpson, Charles F., et al.
Publicado: (1967)

Evaluation of erythroblast macrophage protein related to erythroblastic islands in patients with hematopoietic stem cell transplantation
por: Mao, Xiaolu, et al.
Publicado: (2013)

Differential Proteomic Analysis of Human Erythroblasts Undergoing Apoptosis Induced by Epo-Withdrawal
por: Pellegrin, Stéphanie, et al.
Publicado: (2012)

Ephrin/Eph receptor interaction facilitates macrophage recognition of differentiating human erythroblasts
por: Hampton-O’Neil, Lea A., et al.
Publicado: (2020)

Inhibition of aryl hydrocarbon receptor signaling promotes the terminal differentiation of human erythroblasts
por: Chen, Yijin, et al.
Publicado: (2022)

Differentiation of cancer stem cells into erythroblasts in the presence of CoCl(2)
por: Kumon, Kazuki, et al.
Publicado: (2021)

Phylogenetic and Ontogenetic View of Erythroblastic Islands
por: Giger, Katie M., et al.
Publicado: (2015)

Unraveling Macrophage Heterogeneity in Erythroblastic Islands
por: Seu, Katie Giger, et al.
Publicado: (2017)

Transferrin receptor 1 is required for enucleation of mouse erythroblasts during terminal differentiation
por: Aoto, Mamoru, et al.
Publicado: (2019)

Dexamethasone Predisposes Human Erythroblasts Toward Impaired Lipid Metabolism and Renders Their ex vivo Expansion Highly Dependent on Plasma Lipoproteins
por: Zingariello, Maria, et al.
Publicado: (2019)

Efficient terminal erythroid differentiation requires the APC/C cofactor Cdh1 to limit replicative stress in erythroblasts
por: Cuadrado, Myriam, et al.
Publicado: (2022)

THE FINE STRUCTURE OF THE MID-BODY OF THE RAT ERYTHROBLAST
por: Buck, Robert C., et al.
Publicado: (1962)

Erythroblastic sarcoma in the thoracic cavity of a cow
por: OGASAWARA, Fusae, et al.
Publicado: (2018)

Cholesterol-binding protein TSPO2 coordinates maturation and proliferation of terminally differentiating erythroblasts
por: Kiatpakdee, Benjaporn, et al.
Publicado: (2020)

CD169-CD43 interaction is involved in erythroblastic island formation and erythroid differentiation
por: Bai, Jian, et al.
Publicado: (2023)

Epigenomic analysis of KLF1 haploinsufficiency in primary human erythroblasts
por: Heshusius, Steven, et al.
Publicado: (2022)

Melanocortins Contribute to Sequential Differentiation and Enucleation of Human Erythroblasts via Melanocortin Receptors 1, 2 and 5
por: Simamura, Eriko, et al.
Publicado: (2015)

Cdc42 regulates cell polarization and contractile actomyosin rings during terminal differentiation of human erythroblasts
por: Ubukawa, Kumi, et al.
Publicado: (2020)

Iron Particles in Normal Erythroblasts and Normal and Pathological Erythrocytes
por: Bessis, Marcel C., et al.
Publicado: (1957)

Erythroblast island macrophages: recent discovery and future perspectives
por: Li, Wei, et al.
Publicado: (2019)

B lymphocytes transdifferentiate into immunosuppressive erythroblast-like cells
por: Yang, Zhe, et al.
Publicado: (2023)

Dual Functions of the C5a Receptor as a Connector for the K562 Erythroblast-Like Cell-THP-1 Macrophage-Like Cell Island and as a Sensor for the Differentiation of the K562 Erythroblast-Like Cell during Haemin-Induced Erythropoiesis
por: Nishiura, Hiroshi, et al.
Publicado: (2012)

Glucocorticoids induce differentiation of monocytes towards macrophages that share functional and phenotypical aspects with erythroblastic island macrophages
por: Heideveld, Esther, et al.
Publicado: (2018)

Cytoskeletal distribution and function during the maturation and enucleation of mammalian erythroblasts
Publicado: (1989)

AN ELECTRON MICROSCOPIC STUDY OF NUCLEAR ELIMINATION FROM THE LATE ERYTHROBLAST
por: Skutelsky, Ehud, et al.
Publicado: (1967)

Mitochondrial Atpif1 regulates heme synthesis in developing erythroblasts
por: Shah, Dhvanit I., et al.
Publicado: (2012)

Cannot write session to /tmp/vufind_sessions/sess_drv78e4cc23iqkmco68upfbtut