Effective Therapeutic Approach for Head and Neck Cancer by an Engineered Minibody Targeting the EGFR Receptor

Cetuximab, a chimeric monoclonal antibody developed for targeting the Epidermal Growth Factor Receptor (EGFR), has been intensively used to treat cancer patients with metastatic colorectal cancer and head and neck cancer. Intact immunoglobulin G (IgG) antibody like cetuximab, however, has some limit...

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Detalles Bibliográficos
Autores principales: Kim, Young Pil, Park, Dongsun, Kim, Jae Jin, Choi, Won-Jae, Lee, Sun Hee, Lee, Seo Yun, Kim, Soyeon, Chung, Jee Min, Jeon, Jinseon, Lee, Byoung Dae, Shin, Joo-Ho, Lee, Yun-il, Cho, Hyeseong, Lee, Jeong-Min, Kang, Ho Chul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4249956/
https://www.ncbi.nlm.nih.gov/pubmed/25438047
http://dx.doi.org/10.1371/journal.pone.0113442

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4249956/
https://www.ncbi.nlm.nih.gov/pubmed/25438047
http://dx.doi.org/10.1371/journal.pone.0113442

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