Cargando…

No Evidence of Harms of Probiotic Lactobacillus rhamnosus GG ATCC 53103 in Healthy Elderly—A Phase I Open Label Study to Assess Safety, Tolerability and Cytokine Responses

BACKGROUND: Although Lactobacillus rhamnosus GG ATCC 53103 (LGG) has been consumed by 2 to 5 million people daily since the mid 1990s, there are few clinical trials describing potential harms of LGG, particularly in the elderly. OBJECTIVES: The primary objective of this open label clinical trial is...

Descripción completa

Detalles Bibliográficos
Autores principales:	Hibberd, Patricia L., Kleimola, Lauren, Fiorino, Anne-Maria, Botelho, Christine, Haverkamp, Miriam, Andreyeva, Irina, Poutsiaka, Debra, Fraser, Claire, Solano-Aguilar, Gloria, Snydman, David R.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2014
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4249962/ https://www.ncbi.nlm.nih.gov/pubmed/25438151 http://dx.doi.org/10.1371/journal.pone.0113456

Ejemplares similares

Transcriptomic Profile of Whole Blood Cells from Elderly Subjects Fed Probiotic Bacteria Lactobacillus rhamnosus GG ATCC 53103 (LGG) in a Phase I Open Label Study
por: Solano-Aguilar, Gloria, et al.
Publicado: (2016)

Lactobacillus rhamnosus GG (ATCC 53103) for the Management of Infantile Colic: A Randomized Controlled Trial
por: Savino, Francesco, et al.
Publicado: (2020)

Lactobacillus rhamnosus GG ATCC53103 and Lactobacillus plantarum JL01 improved nitrogen metabolism in weaned piglets by regulating the intestinal flora structure and portal vein metabolites
por: He, Feng, et al.
Publicado: (2023)

Lactobacillus rhamnosus GG as an Effective Probiotic for Murine Giardiasis
por: Goyal, Nisha, et al.
Publicado: (2011)

Anti-Biofilm Properties of Saccharomyces cerevisiae CNCM I-3856 and Lacticaseibacillus rhamnosus ATCC 53103 Probiotics against G. vaginalis
por: Sabbatini, Samuele, et al.
Publicado: (2020)

1681 Randomized Clinical Trial of the Recovery of Probiotics Lactobacillus rhamnosus GG (LGG) and Bifidobacterium animalis subspecies lactis (BB-12) from the Gastrointestinal (GI) Tract of Healthy Volunteers
por: Poutsiaka, Debra D., et al.
Publicado: (2014)

Ribosome Profiling and RNA Sequencing Reveal Genome-Wide Cellular Translation and Transcription Regulation Under Osmotic Stress in Lactobacillus rhamnosus ATCC 53103
por: Fan, Xuejing, et al.
Publicado: (2021)

Lacticaseibacillus rhamnosus ATCC 53103 and Limosilactobacillus reuteri ATCC 53608 Synergistically Boost Butyrate Levels upon Tributyrin Administration Ex Vivo
por: Van den Abbeele, Pieter, et al.
Publicado: (2023)

Ribosome Profiling Reveals Genome-Wide Cellular Translational Regulation in Lacticaseibacillus rhamnosus ATCC 53103 under Acid Stress
por: Fan, Xuejing, et al.
Publicado: (2022)

Antifungal defense of probiotic Lactobacillus rhamnosus GG is mediated by blocking adhesion and nutrient depletion
por: Mailänder-Sánchez, Daniela, et al.
Publicado: (2017)

Probiotic Lactobacillus rhamnosus GG Promotes Mouse Gut Microbiota Diversity and T Cell Differentiation
por: Shi, Chun-wei, et al.
Publicado: (2020)

Lactobacillus GG as an Immune Adjuvant for Live Attenuated Influenza Vaccine in Healthy Adults: A Randomized Double Blind Placebo Controlled Trial
por: Davidson, Lisa E, et al.
Publicado: (2011)

Postbiotic Fractions of Probiotics Lactobacillus plantarum 299v and Lactobacillus rhamnosus GG Show Immune-Modulating Effects
por: Magryś, Agnieszka, et al.
Publicado: (2023)

Stability of Lactobacillus rhamnosus GG in prebiotic edible films
por: Soukoulis, Christos, et al.
Publicado: (2014)

Impact of spray‐drying on the pili of Lactobacillus rhamnosus GG
por: Kiekens, Shari, et al.
Publicado: (2019)

Lactobacillus rhamnosus GG Orchestrates an Antitumor Immune Response
por: Owens, Joshua A., et al.
Publicado: (2021)

Impact of electro-activated whey on growth, acid and bile resistance of Lacticaseibacillus rhamnosus GG and Lactobacillus acidophilus ATCC 4356
por: Aider-Kaci, Farida Ait, et al.
Publicado: (2023)

Inhibition of Streptococcus pneumoniae adherence to human epithelial cells in vitro by the probiotic Lactobacillus rhamnosus GG
por: Wong, Sook-San, et al.
Publicado: (2013)

Using Recombinant Lactococci as an Approach to Dissect the Immunomodulating Capacity of Surface Piliation in Probiotic Lactobacillus rhamnosus GG
por: von Ossowski, Ingemar, et al.
Publicado: (2013)

Preliminary Evaluation of the Safety and Probiotic Potential of Akkermansia muciniphila DSM 22959 in Comparison with Lactobacillus rhamnosus GG
por: Cozzolino, Autilia, et al.
Publicado: (2020)

Interplay between Lactobacillus rhamnosus GG and Candida and the involvement of exopolysaccharides
por: Allonsius, Camille N., et al.
Publicado: (2017)

Combined effect of arginine and fluoride on the growth of Lactobacillus rhamnosus GG
por: Bijle, Mohammed Nadeem, et al.
Publicado: (2021)

Lactobacillus rhamnosus GG modifies the metabolome of pathobionts in gnotobiotic mice
por: Kim, Jinhee, et al.
Publicado: (2021)

Probiotic Lactobacillus rhamnosus GG mono-association suppresses human rotavirus-induced autophagy in the gnotobiotic piglet intestine
por: Wu, Shaoping, et al.
Publicado: (2013)

Personalized B cell response to the Lactobacillus rhamnosus GG probiotic in healthy human subjects: a randomized trial
por: Bornholdt, Jette, et al.
Publicado: (2020)

Influence of fermentation conditions on the surface properties and adhesion of Lactobacillus rhamnosus GG
por: Deepika, Gurjot, et al.
Publicado: (2012)

Towards a better understanding of Lactobacillus rhamnosus GG - host interactions
por: Segers, Marijke E, et al.
Publicado: (2014)

Inhibition of Candida albicans morphogenesis by chitinase from Lactobacillus rhamnosus GG
por: Allonsius, Camille Nina, et al.
Publicado: (2019)

Lactobacillus rhamnosus GG: An Overview to Explore the Rationale of Its Use in Cancer
por: Banna, Giuseppe L., et al.
Publicado: (2017)

Lactobacillus rhamnosus GG Evaluation in Acute Diarrhea (LEAD): An Observational Study
por: Sanklecha, Mukesh, et al.
Publicado: (2022)

833 Lactobacillus GG (LGG) Does Not Eliminate Colonization by Vancomycin Resistant Enterococcus (VRE) in Adults with Comorbidities
por: Doron, Shira, et al.
Publicado: (2014)

L-Lactic Acid Production by Lactobacillus rhamnosus ATCC 10863
por: Senedese, Ana Lívia Chemeli, et al.
Publicado: (2015)

Lipoteichoic acid is an important microbe-associated molecular pattern of Lactobacillus rhamnosus GG
por: Claes, Ingmar JJ, et al.
Publicado: (2012)

Lactobacillus rhamnosus GG Effect on Behavior of Zebrafish During Chronic Ethanol Exposure
por: Schneider, Ana Claudia Reis, et al.
Publicado: (2016)

Lactobacillus rhamnosus GG-Derived Soluble Mediators Modulate Adaptive Immune Cells
por: Ludwig, Irene S., et al.
Publicado: (2018)

Low concentrations of Lactobacillus rhamnosus GG (Yoba(®)) are safe in male Drosophila melanogaster
por: Kasozi, Keneth Iceland, et al.
Publicado: (2019)

Development of Freeze-Thaw Tolerant Lactobacillus rhamnosus GG by Adaptive Laboratory Evolution
por: Kwon, Ye Won, et al.
Publicado: (2018)

Growth Mode and Carbon Source Impact the Surfaceome Dynamics of Lactobacillus rhamnosus GG
por: Savijoki, Kirsi, et al.
Publicado: (2019)

The production and biochemical characterization of α-carbonic anhydrase from Lactobacillus rhamnosus GG
por: Urbański, Linda J., et al.
Publicado: (2022)

Intestinal epithelial cell-derived components regulate transcriptome of Lactobacillus rhamnosus GG
por: Schalich, Kasey, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_2foqn00u29rs1a8qc5u76slqav