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Force Transduction and Lipid Binding in MscL: A Continuum-Molecular Approach
The bacterial mechanosensitive channel MscL, a small protein mainly activated by membrane tension, is a central model system to study the transduction of mechanical stimuli into chemical signals. Mutagenic studies suggest that MscL gating strongly depends on both intra-protein and interfacial lipid-...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Public Library of Science
2014
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4250078/ https://www.ncbi.nlm.nih.gov/pubmed/25437007 http://dx.doi.org/10.1371/journal.pone.0113947 |