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RILP interacts with HOPS complex via VPS41 subunit to regulate endocytic trafficking

The HOPS complex serves as a tethering complex with GEF activity for Ypt7p in yeast to regulate late endosomal membrane maturation. While the role of HOPS complex is well established in yeast cells, its functional and mechanistic aspects in mammalian cells are less well defined. In this study, we re...

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Detalles Bibliográficos
Autores principales: Lin, Xiaosi, Yang, Ting, Wang, Shicong, Wang, Zhen, Yun, Ye, Sun, Lixiang, Zhou, Yunhe, Xu, Xiaohui, Akazawa, Chihiro, Hong, Wanjin, Wang, Tuanlao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4250914/
https://www.ncbi.nlm.nih.gov/pubmed/25445562
http://dx.doi.org/10.1038/srep07282