Paediatric clinical pharmacology in the UK

Paediatric clinical pharmacology is the scientific study of medicines in children and is a relatively new subspecialty in paediatrics in the UK. Training encompasses both the study of the effectiveness of drugs in children (clinical trials) and aspects of drug toxicity (pharmacovigilance). Ethical i...

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Detalles Bibliográficos
Autores principales: Choonara, Imti, Sammons, Helen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2014
Materias:
Drug Therapy
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4251165/
https://www.ncbi.nlm.nih.gov/pubmed/25202131
http://dx.doi.org/10.1136/archdischild-2014-306853
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author Choonara, Imti
Sammons, Helen
author_facet Choonara, Imti
Sammons, Helen
author_sort Choonara, Imti
collection PubMed
description Paediatric clinical pharmacology is the scientific study of medicines in children and is a relatively new subspecialty in paediatrics in the UK. Training encompasses both the study of the effectiveness of drugs in children (clinical trials) and aspects of drug toxicity (pharmacovigilance). Ethical issues in relation to clinical trials and also studies of the pharmacokinetics and drug metabolism in children are crucial. Paediatric patients require formulations that young children in particular are able to take. The scientific evidence generated from clinical trials, pharmacokinetic studies and studies of drug toxicity all need to be applied in order to ensure that medicines are used rationally in children.
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spelling pubmed-42511652014-12-04 Paediatric clinical pharmacology in the UK Choonara, Imti Sammons, Helen Arch Dis Child Drug Therapy Paediatric clinical pharmacology is the scientific study of medicines in children and is a relatively new subspecialty in paediatrics in the UK. Training encompasses both the study of the effectiveness of drugs in children (clinical trials) and aspects of drug toxicity (pharmacovigilance). Ethical issues in relation to clinical trials and also studies of the pharmacokinetics and drug metabolism in children are crucial. Paediatric patients require formulations that young children in particular are able to take. The scientific evidence generated from clinical trials, pharmacokinetic studies and studies of drug toxicity all need to be applied in order to ensure that medicines are used rationally in children. BMJ Publishing Group 2014-12 2014-09-08 /pmc/articles/PMC4251165/ /pubmed/25202131 http://dx.doi.org/10.1136/archdischild-2014-306853 Text en Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://group.bmj.com/group/rights-licensing/permissions This is an Open Access article distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
spellingShingle Drug Therapy
Choonara, Imti
Sammons, Helen
Paediatric clinical pharmacology in the UK
title Paediatric clinical pharmacology in the UK
title_full Paediatric clinical pharmacology in the UK
title_fullStr Paediatric clinical pharmacology in the UK
title_full_unstemmed Paediatric clinical pharmacology in the UK
title_short Paediatric clinical pharmacology in the UK
title_sort paediatric clinical pharmacology in the uk
topic Drug Therapy
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4251165/
https://www.ncbi.nlm.nih.gov/pubmed/25202131
http://dx.doi.org/10.1136/archdischild-2014-306853
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