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The stem cell organisation, and the proliferative and gene expression profile of Barrett's epithelium, replicates pyloric-type gastric glands

OBJECTIVE: Barrett's oesophagus shows appearances described as ‘intestinal metaplasia’, in structures called ‘crypts’ but do not typically display crypt architecture. Here, we investigate their relationship to gastric glands. METHODS: Cell proliferation and migration within Barrett's gland...

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Detalles Bibliográficos
Autores principales: Lavery, Danielle L, Nicholson, Anna M, Poulsom, Richard, Jeffery, Rosemary, Hussain, Alia, Gay, Laura J, Jankowski, Janusz A, Zeki, Sebastian S, Barr, Hugh, Harrison, Rebecca, Going, James, Kadirkamanathan, Sritharan, Davis, Peter, Underwood, Timothy, Novelli, Marco R, Rodriguez–Justo, Manuel, Shepherd, Neil, Jansen, Marnix, Wright, Nicholas A, McDonald, Stuart A C
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4251192/
https://www.ncbi.nlm.nih.gov/pubmed/24550372
http://dx.doi.org/10.1136/gutjnl-2013-306508